54903-61-6

Basic information

• Product Name: 6-Acetyl-3-methylbenzoxazol-2(3H)-one
• Synonyms: 6-Acetyl-3-methylbenzoxazol-2(3H)-one
• CAS NO: 54903-61-6
• Molecular Formula: C₁₀H₉NO₃
• Molecular Weight: 191.1834
• Mol File: 54903-61-6.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 332.5°Cat760mmHg
• Flash Point: 154.9°C
• Appearance: /
• Density: 1.286g/cm³
• Vapor Pressure: 0.000145mmHg at 25°C
• Refractive Index: 1.576
• CAS DataBase Reference: 6-Acetyl-3-methylbenzoxazol-2(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Acetyl-3-methylbenzoxazol-2(3H)-one(54903-61-6)
• EPA Substance Registry System: 6-Acetyl-3-methylbenzoxazol-2(3H)-one(54903-61-6)

Safety Data

• Hazardous Substances Data: 54903-61-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H9NO3/c1-6(12)7-3-4-8-9(5-7)14-10(13)11(8)2/h3-5H,1-2H3

Upstream product

• 21892-80-8 3-methylbenzo[d]oxazol-2(3H)-one 
• 75-36-5 acetyl chloride 
• 108-24-7 acetic anhydride 
• 64-19-7 acetic acid 
• 95-55-6 2-amino-phenol 
• 54903-09-2 6-acetyl-3H-benzooxazol-2-one 
• 74-88-4 methyl iodide 

Downstream Products

• 54903-57-0 3-hydroxy-4-methylaminoacetophenone 
• 80427-88-9 6-(p-chloro-cinnamoyl)-3-methylbenzoxazolinone 
• 80427-87-8 6-cinnamoyl-3-methylbenzoxazolinone 
• 83297-64-7 3-Methyl-6-[(E)-(3-phenyl-acryloyl)]-3H-benzooxazol-2-one 
• 80428-00-8 2,7-dioxo-3-methyl-5-phenyl-2,3,5,6-tetrahydrocyclopentabenzoxazole 
• 134541-21-2 3-methyl-7-oximino-2-oxo-5-phenyl-2,3,5,6-tetrahydrocyclopentabenzoxazole 
• 183488-18-8 5-(2-Chloro-phenyl)-3-methyl-5,6-dihydro-3H-indeno[5,6-d]oxazole-2,7-dione 
• 183488-19-9 5-(2-Chloro-phenyl)-3-methyl-5,6-dihydro-3H-indeno[5,6-d]oxazole-2,7-dione 7-oxime 
• 131363-33-2 3-methyl-6-{3-[4-(3-trifluoromethylphenyl)-1-piperazinyl]-1-oxopropyl}benzoxazolinone 
• 1393571-57-7 6-(4-((E)-3-(4-(4-tolyl)piperazin-1-yl)-3-oxoprop-1-enyl)-1-phenyl-1H-pyrazole-3-yl)-3-methyl-2-oxo-3H-benzoxazolone 
• 1393571-58-8 6-(4-((E)-3-(4-(4-(trifluoromethyl)phenyl)piperazin-1-yl)-3-oxoprop-1-enyl)-1-phenyl-1H-pyrazole-3-yl)-3-methyl-2-oxo-3H-benzoxazolone 
• 1393571-59-9 6-(4-((E)-3-(4-(4-methylbenzyl)piperazin-1-yl)-3-oxoprop-1-enyl)-1-phenyl-1H-pyrazole-3-yl)-3-methyl-2-oxo-3H-benzoxazolone 
• 1393571-60-2 6-(4-((E)-3-(4-(4-(trifluoromethyl)benzyl)piperazin-1-yl)-3-oxoprop-1-enyl)-1-phenyl-1H-pyrazole-3-yl)-3-methyl-2-oxo-3H-benzoxazolone 
• 1393571-48-6 3-(2,3-dihydro-3-methyl-2-oxo-3H-benzoxazole-6-yl)-1-phenyl-1H-pyrazole-4-carboxyaldehyde 

Relevant articles and documents

Synthesis and structure-activity relationship of aminoarylthiazole derivatives as potential potentiators of the chloride transport defect in cystic fibrosis

Background: Cystic fibrosis (CF) is the autosomal recessive disorder most common in Caucasian populations. It is caused by mutations in the cystic fibrosis transmembrane regulator protein (CFTR). CFTR is predominantly expressed at the apical plasma membra

Synthesis, anti-inflammatory, antiplatelet and in silico ealuations of (E)-3-(3-(2,3-dihydro-3-methyl-2-oxo-3H-benzoxazole-6-yl)-1-phenyl-1H-pyrazole- 4-yl)acrylamides

A series of (E) -3-(3-(2,3-dihydro-3-methyl-2-oxo-3H -benzoxazole-6-yl)-1- phenyl-1H -pyrazole-4-yl)acrylamides (7a-k) were synthesized and ealuated for their in itro inhibitory actiities on COX-1 and COX-2 isoforms using a human whole blood assay as well as their antiplatelet profile against human platelet aggregation using arachidonic acid as agonists. Among the synthesized deriaties 7a-k, especially compound 7g exhibited dual anti-inflammatory and antiplatelet actiity with selectie COX-2 inhibition. TUeBITAK.

Synthesis of 1,11-dihydro-2H-[1,3]oxazolo[4′,5′:5,6]indeno[1,2- b]quinolin-2-ones with potential topoisomerase I inhibitory activity

A series of 1,11-dihydro-2,11-[1,3]oxazolo[4′,5′:5,6]indeno[1, 2-b]quinolin-2-ones were prepared by means of Friedlaender condensations. The starting materials for the preparations were commercial substituted-2- aminoacetophenones and various 5,6-dihydro-2H-indeno[5,6-d][l,3]oxazole-2,7(3H)- diones that were synthesized from 2(3H)-benzoxazolones or their N-methyl analogues. Thieme Verlag Stuttgart.