4H-Indazol-4-one, 2,5,6,7-tetrahydro-2-phenyl-

Base Information

• Chemical Name: 4H-Indazol-4-one, 2,5,6,7-tetrahydro-2-phenyl-
• CAS No.: 113502-44-6
• Molecular Formula: C13H12N2O
• Molecular Weight: 212.251
• Mol file: 113502-44-6.mol

Synonyms:2-phenyl-2,5,6,7-tetrahydro-indazol-4-one;tetrahydro-2,5,6,7 phenyl-2 indazolone-4;2-Phenyl-4-oxo-4,5,6,7-tetrahydro(2H)indazol;

Chemical Property of 4H-Indazol-4-one, 2,5,6,7-tetrahydro-2-phenyl-

Chemical Property:

• Boiling Point: 378.2±11.0 °C(Predicted)
• PSA: 34.89000
• Density: 1.25±0.1 g/cm3(Predicted)
• LogP: 2.39130

Purity/Quality:

2-Phenyl-4,5,6,7-tetrahydro-2h-indazol-4-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4H-Indazol-4-one, 2,5,6,7-tetrahydro-2-phenyl-

There total 3 articles about 4H-Indazol-4-one, 2,5,6,7-tetrahydro-2-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

cyclohexane-1,3-dione monophenylhydrazone (27385-45-1) + N,N-dimethyl-formamide dimethyl acetal (4637-24-5) → 2-phenyl-6,7-dihydro-2H-indazol-4(5H)-one (113502-44-6)

Guidance literature:

In tetrahydrofuran; for 16h; Heating;

DOI:10.1055/s-2008-1032086

Reference yield:

phenylhydrazine (100-63-0) + 2-(methylthio)-7,8-dihydroquinazolin-5(6H)-one (21599-35-9) → 2-phenyl-6,7-dihydro-2H-indazol-4(5H)-one (113502-44-6)

Guidance literature:

With hydrogenchloride; In methanol; for 5h; Heating;

Reference yield:

→ 2-phenyl-6,7-dihydro-2H-indazol-4(5H)-one (113502-44-6)

Guidance literature:

Cyclohexan-1,3-dion-monophenylhydrazon, Orthoameisensaeure-triethylester, Toluol, p-Toluolsulfonsaeure;

DOI:10.1021/jo00955a039

upstream raw materials:

phenylhydrazine

2-(methylthio)-7,8-dihydroquinazolin-5(6H)-one

cyclohexane-1,3-dione monophenylhydrazone

N,N-dimethyl-formamide dimethyl acetal

Downstream raw materials:

methyl 6-(4-methoxyphenyl)-8-(methylthio)-2-phenyl-4,5-dihydro-2H-benzo[e]indazole-9-carboxylate

methyl 8-(methylthio)-2,6-diphenyl-4,5-dihydro-2H-benzo[e]indazole-9-carboxylate

methyl 8-(methylthio)-2-phenyl-6-p-tolyl-4,5-dihydro-2H-benzo[e]indazole-9-carboxylate

methyl 6-(4-chlorophenyl)-8-(methylthio)-2-phenyl-4,5-dihydro-2H-benzo[e]indazole-9-carboxylate