N-(2-hydroxyethyl)-2-(4-methoxyphenyl)ethanamine

Base Information

Chemical Name:N-(2-hydroxyethyl)-2-(4-methoxyphenyl)ethanamine
CAS No.:113733-05-4
Molecular Formula:C11H17NO2
Molecular Weight:195.261
Hs Code.:
DSSTox Substance ID:DTXSID30601605
Wikidata:Q82498361
Mol file:113733-05-4.mol

Synonyms:113733-05-4;N-(2-hydroxyethyl)-2-(4-methoxyphenyl)ethanamine;SCHEMBL8880193;DTXSID30601605;FJTUVJSRRMLGNP-UHFFFAOYSA-N;AKOS000256100;2-{[2-(4-Methoxyphenyl)ethyl]amino}ethan-1-ol

Suppliers and Price of N-(2-hydroxyethyl)-2-(4-methoxyphenyl)ethanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of N-(2-hydroxyethyl)-2-(4-methoxyphenyl)ethanamine

Chemical Property:

XLogP3:1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:195.125928785
Heavy Atom Count:14
Complexity:133

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)CCNCCO

Technology Process of N-(2-hydroxyethyl)-2-(4-methoxyphenyl)ethanamine

There total 4 articles about N-(2-hydroxyethyl)-2-(4-methoxyphenyl)ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.5%

: 5107-52-8
2-(p-methoxyphenyl)ethyl toluene-p-sulphonate

: 141-43-5
ethanolamine

: 113733-05-4
2-[2-(4-methoxyphenyl)ethylamino]ethanol

Guidance literature:: With sodium carbonate; potassium iodide; In N,N-dimethyl-formamide; at 80 ℃; for 1h;
DOI:10.1021/acs.jmedchem.0c02261

Reference yield: 92.0%

: 141-43-5
ethanolamine

: 73735-36-1
methanesulfonic acid-2-(4-methoxyphenyl)ethyl ester

: 113733-05-4
2-[2-(4-methoxyphenyl)ethylamino]ethanol

Guidance literature:: With triethylamine; In tetrahydrofuran; at 20 ℃;
DOI:10.1016/j.bmcl.2012.10.067

Reference yield:

: 856439-23-1
N-[2-(tert-butyldimethylsilanyloxy)ethyl]-2-(4-methoxyphenyl)acetamide

: 113733-05-4
2-[2-(4-methoxyphenyl)ethylamino]ethanol

Guidance literature:: Multi-step reaction with 2 steps

1: tetra-n-butylammonium fluoride / tetrahydrofuran / 1 h / 25 °C

2: 80 mg / LiAlH₄ / tetrahydrofuran / cooling

With lithium aluminium tetrahydride; tetrabutyl ammonium fluoride; In tetrahydrofuran;
DOI:10.1016/j.bmc.2005.03.004