(2S,4S)-4-PHENOXY-PYRROLIDINE-2-CARBOXYLIC ACID METHYL ESTER

Base Information

Chemical Name:(2S,4S)-4-PHENOXY-PYRROLIDINE-2-CARBOXYLIC ACID METHYL ESTER
CAS No.:113949-37-4
Molecular Formula:C11H13NO3
Molecular Weight:207.229
Hs Code.:
Mol file:113949-37-4.mol

Synonyms:(2S,4S)-4-Phenoxy-pyrrolidine-2-carboxylic acid;L-Proline, 4-phenoxy-, cis-;

Suppliers and Price of (2S,4S)-4-PHENOXY-PYRROLIDINE-2-CARBOXYLIC ACID METHYL ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of (2S,4S)-4-PHENOXY-PYRROLIDINE-2-CARBOXYLIC ACID METHYL ESTER

Chemical Property:

Vapor Pressure:0mmHg at 25°C
PSA：58.56000
LogP:1.20930

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (2S,4S)-4-PHENOXY-PYRROLIDINE-2-CARBOXYLIC ACID METHYL ESTER

There total 1 articles about (2S,4S)-4-PHENOXY-PYRROLIDINE-2-CARBOXYLIC ACID METHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 132592-07-5
(2S,4S)-4-hydroxy-1,2-pyrrolidinedicarboxylic acid 1,2-bis(phenylmethyl ester)

: 108-95-2,27073-41-2
phenol

: 113949-37-4
cis-4-phenoxy-L-propline

Guidance literature:: With hydrogen; triphenylphosphine; diethylazodicarboxylate; palladium on activated charcoal; Yield given. Multistep reaction; 1.) THF, room temperature, overnight;
DOI:10.1021/jm00401a014

Reference yield:

: 74345-73-6
(2R,S)-3-Acetylthio-2-methylpropanoyl chloride

: 113949-37-4
cis-4-phenoxy-L-propline

: 113949-46-5
(2S,4S)-1-((S)-3-Acetylsulfanyl-2-methyl-propionyl)-4-phenoxy-pyrrolidine-2-carboxylic acid

Guidance literature:: With sodium carbonate; In water; for 1h;
DOI:10.1021/jm00401a014

Reference yield:

: 113949-37-4
cis-4-phenoxy-L-propline

: 113949-49-8
(2S,4S)-1-((S)-3-Mercapto-2-methyl-propionyl)-4-phenoxy-pyrrolidine-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 25percent sodium carbonate, pH 8.5 / H₂O / 1 h

2: ammonia / H₂O / 2 h

With ammonia; sodium carbonate; In water;
DOI:10.1021/jm00401a014