N(alpha)-(Diphenoxyphosphoryl)alanylproline

Base Information

Chemical Name:N(alpha)-(Diphenoxyphosphoryl)alanylproline
CAS No.:97280-40-5
Molecular Formula:C32H46N3O6P
Molecular Weight:0
Hs Code.:
DSSTox Substance ID:DTXSID10914023
Mol file:97280-40-5.mol

Synonyms:DDP-Ala-Pro;N(alpha)-(diphenoxyphosphoryl)alanylproline;N(alpha)-diphenoxyphosphoryl-L-alanyl-L-proline

Suppliers and Price of N(alpha)-(Diphenoxyphosphoryl)alanylproline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of N(alpha)-(Diphenoxyphosphoryl)alanylproline

Chemical Property:

Vapor Pressure:1.45E-15mmHg at 25°C
Melting Point:117 - 121 °C
Boiling Point:606.6°Cat760mmHg
Flash Point:320.6°C
PSA：127.01000
Density:g/cm³
LogP:7.26730
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:10
Exact Mass:599.31242319
Heavy Atom Count:42
Complexity:710

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C(=O)N1CCCC1C(=O)O)NP(=O)(OC2=CC=CC=C2)OC3=CC=CC=C3.C1CCC(CC1)NC2CCCCC2
Isomeric SMILES:C[C@H](C(=O)N1CCC[C@H]1C(=O)O)NP(=O)(OC2=CC=CC=C2)OC3=CC=CC=C3.C1CCC(CC1)NC2CCCCC2

Technology Process of N(alpha)-(Diphenoxyphosphoryl)alanylproline

There total 3 articles about N(alpha)-(Diphenoxyphosphoryl)alanylproline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 74406-94-3
N^α-(diphenoxyphosphoryl)-L-alanyl-L-proline benzyl ester

: 101-83-7
N-cyclohexyl-cyclohexanamine

: 97280-40-5
N^α-(diphenoxyphosphoryl)-L-alanyl-L-proline dicyclobenzylamine salt

Guidance literature:: With hydrogen; palladium on activated charcoal; 1.) ethanol, 1 h;
DOI:10.1021/jm00148a008

Reference yield:

: 41591-35-9
benzyl (L)-alanyl-(L)-prolinate hydrochloride

: 97280-40-5
N^α-(diphenoxyphosphoryl)-L-alanyl-L-proline dicyclobenzylamine salt

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / N-ethylmorpholine / CH₂Cl₂ / 20 h / 4 °C

2: 90 percent / 1.) H₂, / 1.) 5percent Pd/C / 1.) ethanol, 1 h

With N-ethylmorpholine;; hydrogen; palladium on activated charcoal; In dichloromethane;
DOI:10.1021/jm00148a008

Reference yield:

: 2524-64-3
chlorophosphoric acid diphenyl ester

: 97280-40-5
N^α-(diphenoxyphosphoryl)-L-alanyl-L-proline dicyclobenzylamine salt

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / N-ethylmorpholine / CH₂Cl₂ / 20 h / 4 °C

2: 90 percent / 1.) H₂, / 1.) 5percent Pd/C / 1.) ethanol, 1 h

With N-ethylmorpholine;; hydrogen; palladium on activated charcoal; In dichloromethane;
DOI:10.1021/jm00148a008