Technology Process of Taxifolin 6-C-glucoside
There total 20 articles about Taxifolin 6-C-glucoside which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: Resolution of racemate
2: scandium tris(trifluoromethanesulfonate) / water; acetonitrile / 48 h / Inert atmosphere; Reflux
With
scandium tris(trifluoromethanesulfonate);
In
water; acetonitrile;
DOI:10.1055/s-0040-1707971
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sodium hydroxide; dihydrogen peroxide / methanol / 5 h / 20 °C / Inert atmosphere
2: hydrogenchloride / methanol; water; tetrahydrofuran / 2 h / 55 °C / Inert atmosphere
3: Resolution of racemate
4: scandium tris(trifluoromethanesulfonate) / water; acetonitrile / 48 h / Inert atmosphere; Reflux
With
hydrogenchloride; dihydrogen peroxide; sodium hydroxide; scandium tris(trifluoromethanesulfonate);
In
tetrahydrofuran; methanol; water; acetonitrile;
DOI:10.1055/s-0040-1707971
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: sodium hydride / N,N-dimethyl-formamide / 0.17 h / 0 °C / Inert atmosphere
1.2: 5 h / -5 °C / Inert atmosphere
2.1: trifluoromethylsulfonic anhydride / dichloromethane / 0.08 h / -5 °C / Inert atmosphere
2.2: -5 °C / Inert atmosphere
3.1: sodium hydroxide; dihydrogen peroxide / methanol / 5 h / 20 °C / Inert atmosphere
4.1: hydrogenchloride / methanol; water; tetrahydrofuran / 2 h / 55 °C / Inert atmosphere
5.1: Resolution of racemate
6.1: scandium tris(trifluoromethanesulfonate) / water; acetonitrile / 48 h / Inert atmosphere; Reflux
With
hydrogenchloride; trifluoromethylsulfonic anhydride; dihydrogen peroxide; sodium hydride; sodium hydroxide; scandium tris(trifluoromethanesulfonate);
In
tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1055/s-0040-1707971