Taxifolin 6-C-glucoside

Base Information

Chemical Name:Taxifolin 6-C-glucoside
CAS No.:112494-39-0
Molecular Formula:C21H22 O12
Molecular Weight:466.39
Hs Code.:
DSSTox Substance ID:DTXSID10150065
Nikkaji Number:J3.041.280J
Wikidata:Q83015997
Mol file:112494-39-0.mol

Synonyms:taxifolin 6-C-glucoside

Suppliers and Price of Taxifolin 6-C-glucoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Taxifolin 6-C-glucoside

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:914.7°Cat760mmHg
Flash Point:320.9°C
PSA：217.60000
Density:1.79g/cm³
LogP:-1.29880
XLogP3:-1
Hydrogen Bond Donor Count:9
Hydrogen Bond Acceptor Count:12
Rotatable Bond Count:3
Exact Mass:466.11112613
Heavy Atom Count:33
Complexity:707

Purity/Quality:: 98.0% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1C2C(C(=O)C3=C(O2)C=C(C(=C3O)C4C(C(C(C(O4)CO)O)O)O)O)O)O)O
Isomeric SMILES:C1=CC(=C(C=C1[C@@H]2[C@H](C(=O)C3=C(O2)C=C(C(=C3O)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)O)O)O

Technology Process of Taxifolin 6-C-glucoside

There total 20 articles about Taxifolin 6-C-glucoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 480-18-2,24198-97-8,98006-93-0,111003-33-9,114761-89-6,17654-26-1,5117-01-1
(+/-)-taxifolin

: 112494-39-0
(2R,3R)-(+)-3',4',5,7-tetrahydroxydihydroflavonol-6-C-β-D-glucopyranoside

Guidance literature:: Multi-step reaction with 2 steps

1: Resolution of racemate

2: scandium tris(trifluoromethanesulfonate) / water; acetonitrile / 48 h / Inert atmosphere; Reflux

With scandium tris(trifluoromethanesulfonate); In water; acetonitrile;
DOI:10.1055/s-0040-1707971

Reference yield:

: 36804-12-3
(E)-3-(3,4-bis(methoxymethoxy)phenyl)-1-(2,4,6-tris(methoxymethoxy)phenyl)-prop-2-en-1-one

: 112494-39-0
(2R,3R)-(+)-3',4',5,7-tetrahydroxydihydroflavonol-6-C-β-D-glucopyranoside

Guidance literature:: Multi-step reaction with 4 steps

1: sodium hydroxide; dihydrogen peroxide / methanol / 5 h / 20 °C / Inert atmosphere

2: hydrogenchloride / methanol; water; tetrahydrofuran / 2 h / 55 °C / Inert atmosphere

3: Resolution of racemate

4: scandium tris(trifluoromethanesulfonate) / water; acetonitrile / 48 h / Inert atmosphere; Reflux

With hydrogenchloride; dihydrogen peroxide; sodium hydroxide; scandium tris(trifluoromethanesulfonate); In tetrahydrofuran; methanol; water; acetonitrile;
DOI:10.1055/s-0040-1707971

Reference yield:

: 108-73-6
3,5-dihydroxyphenol

: 112494-39-0
(2R,3R)-(+)-3',4',5,7-tetrahydroxydihydroflavonol-6-C-β-D-glucopyranoside

Guidance literature:: Multi-step reaction with 6 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 0.17 h / 0 °C / Inert atmosphere

1.2: 5 h / -5 °C / Inert atmosphere

2.1: trifluoromethylsulfonic anhydride / dichloromethane / 0.08 h / -5 °C / Inert atmosphere

2.2: -5 °C / Inert atmosphere

3.1: sodium hydroxide; dihydrogen peroxide / methanol / 5 h / 20 °C / Inert atmosphere

4.1: hydrogenchloride / methanol; water; tetrahydrofuran / 2 h / 55 °C / Inert atmosphere

5.1: Resolution of racemate

6.1: scandium tris(trifluoromethanesulfonate) / water; acetonitrile / 48 h / Inert atmosphere; Reflux

With hydrogenchloride; trifluoromethylsulfonic anhydride; dihydrogen peroxide; sodium hydride; sodium hydroxide; scandium tris(trifluoromethanesulfonate); In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1055/s-0040-1707971