2-(DIMETHYLAMINO)-6-PHENYL-4-(TRIFLUOROMETHYL)NICOTINONITRILE

Base Information

• Chemical Name: 2-(DIMETHYLAMINO)-6-PHENYL-4-(TRIFLUOROMETHYL)NICOTINONITRILE
• CAS No.: 114084-96-7
• Molecular Formula: C₁₅H₁₂F₃N₃
• Molecular Weight: 291.276
• Mol file: 114084-96-7.mol

Synonyms:2-Dimethylamino-6-phenyl-4-trifluoromethyl-nicotinonitrile;

Chemical Property of 2-(DIMETHYLAMINO)-6-PHENYL-4-(TRIFLUOROMETHYL)NICOTINONITRILE

Chemical Property:

• PSA: 39.92000
• LogP: 3.70508

Purity/Quality:

2-(Dimethylamino)-6-phenyl-4-(trifluoromethyl)nicotinonitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(DIMETHYLAMINO)-6-PHENYL-4-(TRIFLUOROMETHYL)NICOTINONITRILE

There total 2 articles about 2-(DIMETHYLAMINO)-6-PHENYL-4-(TRIFLUOROMETHYL)NICOTINONITRILE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

4-trifluoromethyl-6-phenyl-2-chloro-3-cyanopyridine (114084-91-2) + dimethyl amine (124-40-3) → 2-(N,N-dimethylamino)-4-trifluoromethyl-6-phenyl-3-cyanopyridine (114084-96-7)

Guidance literature:

In ethanol; for 1h; Heating;

DOI:10.1007/BF00475366

Reference yield:

2-oxo-6-phenyl-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile (3335-44-2) → 2-(N,N-dimethylamino)-4-trifluoromethyl-6-phenyl-3-cyanopyridine (114084-96-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / POCl₃, DMF / 8 h / 130 °C

2: 74 percent / ethanol / 1 h / Heating

With N,N-dimethyl-formamide; trichlorophosphate; In ethanol;

DOI:10.1007/BF00475366

upstream raw materials:

4-trifluoromethyl-6-phenyl-2-chloro-3-cyanopyridine

dimethyl amine

2-oxo-6-phenyl-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 114084-96-7 2-(DIMETHYLAMINO)-6-PHENYL-4-(TRIFLUOROMETHYL)NICOTINONITRILE

Send

Send

Metric Ton KG G Pound L ML

Send

Send