2-Aminopropanol hydrochloride

Base Information

• Chemical Name: 2-Aminopropanol hydrochloride
• CAS No.: 6170-23-6
• Deprecated CAS: 17016-92-1
• Molecular Formula: C3H9 N O . Cl H
• Molecular Weight: 111.572
• Hs Code.: 2922199090
• European Community (EC) Number: 228-215-7
• UNII: PQC204N04O
• DSSTox Substance ID: DTXSID70276093,DTXSID70884233
• Wikidata: Q27286713
• Mol file: 6170-23-6.mol

Synonyms:2-aminopropanol hydrochloride;17016-92-1;DL-Alaninol hydrochloride;6170-23-6;2-Aminopropan-1-ol hydrochloride;1-Propanol, 2-amino-, hydrochloride;1-Propanol, 2-amino-, hydrochloride (1:1);2-aminopropan-1-ol;hydrochloride;Dl-alaninolhydrochloride;UNII-PQC204N04O;PQC204N04O;EINECS 228-215-7;AI3-52543;Alaninol hydrochloride;C3H9NO.ClH;SCHEMBL3463781;DTXSID70276093;DTXSID70884233;AKOS015911785;HY-W141854;SB46696;2-AMINOPROPANOL HYDROCHLORIDE [MI];L-ASPARTIC ACID 4-METHYL ESTER HCL;CS-0201650;FT-0637472;2-AMINOPROPANOL HYDROCHLORIDE, (+/-)-;DL-Alaninol hydrochloride, >=98%, crystalline;Q27286713

Chemical Property of 2-Aminopropanol hydrochloride

Chemical Property:

• PSA: 46.25000
• LogP: 0.82820
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 111.0450916
• Heavy Atom Count: 6
• Complexity: 22.9

Purity/Quality:

99% ^*data from raw suppliers

2-Amino-1-propanolHCl 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(CO)N.Cl

Technology Process of 2-Aminopropanol hydrochloride

There total 1 articles about 2-Aminopropanol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

2,2,2-trichloro-acetimidic acid propyl ester (99418-53-8) → dl-2-amino-1-propanol hydrochloride (6170-23-6,17016-92-1)

Guidance literature:

2,2,2-trichloro-acetimidic acid propyl ester; With N-iodo-succinimide; In 1,2-dichloro-ethane; at 110 ℃; for 3h; Inert atmosphere; Sealed tube;

With hydrogenchloride; In tetrahydrofuran; water; 1,2-dichloro-ethane; at 20 ℃; for 5h; Inert atmosphere; Sealed tube;

DOI:10.1039/c7cc08897c

Reference yield:

dl-2-amino-1-propanol hydrochloride (6170-23-6,17016-92-1) + methyloxirane (75-56-9,16033-71-9) → bis(2-hydroxy-1-methylethyl)amine (2294-46-4)

Guidance literature:

With sodium hydroxide; In methanol;

Reference yield:

2-(2-bromoacetamido)-5-chloro-benzophenone (32580-26-0) + base 5-chloro-2[ 1-hydroxy-2-propylamino)acetamido]benzophenone + dl-2-amino-1-propanol hydrochloride (6170-23-6,17016-92-1) → oxazolam (29912-93-4)

Guidance literature:

With hydrogenchloride; triethylamine; In pyridine; ethanol; hexane; ethyl acetate;

upstream raw materials:

2,2,2-trichloro-acetimidic acid propyl ester

Downstream raw materials:

oxazolam

bis(2-hydroxy-1-methylethyl)amine