Benzamide, N-[3-[[[[2,3-bis(phenylmethoxy)benzoyl]amino]acetyl][4-[[2,3-bis(phenyl methoxy)benzoyl]amino]butyl]amino]propyl]-2,3-bis(phenylmethoxy)-

Base Information

• Chemical Name: Benzamide, N-[3-[[[[2,3-bis(phenylmethoxy)benzoyl]amino]acetyl][4-[[2,3-bis(phenyl methoxy)benzoyl]amino]butyl]amino]propyl]-2,3-bis(phenylmethoxy)-
• CAS No.: 114482-48-3
• Molecular Formula: C72H70N4O10
• Molecular Weight: 1151.37
• Mol file: 114482-48-3.mol

Synonyms:

Chemical Property of Benzamide, N-[3-[[[[2,3-bis(phenylmethoxy)benzoyl]amino]acetyl][4-[[2,3-bis(phenyl methoxy)benzoyl]amino]butyl]amino]propyl]-2,3-bis(phenylmethoxy)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzamide, N-[3-[[[[2,3-bis(phenylmethoxy)benzoyl]amino]acetyl][4-[[2,3-bis(phenyl methoxy)benzoyl]amino]butyl]amino]propyl]-2,3-bis(phenylmethoxy)-

There total 8 articles about Benzamide, N-[3-[[[[2,3-bis(phenylmethoxy)benzoyl]amino]acetyl][4-[[2,3-bis(phenyl methoxy)benzoyl]amino]butyl]amino]propyl]-2,3-bis(phenylmethoxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

N-(2,3-dibenzyloxybenzoyl)glycine (74272-80-3) + 2,3-bis(benzyloxy)-N-(3-(4-(2,3-bis(benzyloxy)benzamido)butylamino)propyl)benzamide (74272-81-4) → N-<3-(2,3-dibenzyloxybenzoylamino)propyl>-N-<4-(2,3-dibenzyloxybenzoylamino)butyl>-N-2,3-dibenzyloxybenzoylglycylamide (114482-48-3)

Guidance literature:

With dmap; diphenylphosphoranyl azide; triethylamine; In N,N-dimethyl-formamide; for 48h; Ambient temperature;

Reference yield:

2,3-bis(benzyloxy)benzoyl chloride (69146-58-3) → N-<3-(2,3-dibenzyloxybenzoylamino)propyl>-N-<4-(2,3-dibenzyloxybenzoylamino)butyl>-N-2,3-dibenzyloxybenzoylglycylamide (114482-48-3)

Guidance literature:

Multi-step reaction with 3 steps

2: aq. sodium hydroxide

3: 84 percent / 1.) diphenylphosphoryl azide; 2.) triethylamine, dimethylaminopyridine / dimethylformamide / 1.) 0 deg C; 2.) rt., 2 d

With dmap; sodium hydroxide; diphenylphosphoranyl azide; triethylamine; In N,N-dimethyl-formamide;

DOI:10.1016/S0040-4020(01)85669-6

Reference yield:

dibenzyloxybenzoyl glycine methyl ester (945496-82-2) → N-<3-(2,3-dibenzyloxybenzoylamino)propyl>-N-<4-(2,3-dibenzyloxybenzoylamino)butyl>-N-2,3-dibenzyloxybenzoylglycylamide (114482-48-3)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. sodium hydroxide

2: 84 percent / 1.) diphenylphosphoryl azide; 2.) triethylamine, dimethylaminopyridine / dimethylformamide / 1.) 0 deg C; 2.) rt., 2 d

With dmap; sodium hydroxide; diphenylphosphoranyl azide; triethylamine; In N,N-dimethyl-formamide;

DOI:10.1016/S0040-4020(01)85669-6

upstream raw materials:

N-(2,3-dibenzyloxybenzoyl)glycine

2,3-bis(benzyloxy)-N-(3-(4-(2,3-bis(benzyloxy)benzamido)butylamino)propyl)benzamide

2,3-bis(benzyloxy)benzoyl chloride

dibenzyloxybenzoyl glycine methyl ester

Downstream raw materials:

N⁴--N¹,N⁸-bis(2,3-dihydroxybenzoyl)spermidine