69146-58-3Relevant articles and documents
Total synthesis and structure revision of mirubactin, and its iron binding activity
Kishimoto, Shinji,Nishimura, Shinichi,Kakeya, Hideaki
, p. 1303 - 1305 (2015)
Dechloro-chlorocatechelin A (3), a deschloro-derivative of a microbial siderophore chlorocatechelin A (2), was synthesized from 2,3-dihydroxybenzoic acid, D-arginine, and 1-benzyl Dglutamate. The spectral data were unambiguously identical with those of mi
PEPTOID-BASED CHELATING LIGANDS FOR SELECTIVE METAL CHELATION
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, (2020/04/29)
The present disclosure provides peptoid-based chelating ligands, corresponding cyclic peptoids, and methods of making thereof. Functional groups may be tailored for high metal binding affinity and selectivity. The side chains of a cyclic peptoid according to the present disclosure may be selected based on, for example, high affinity for actinide or other metal ions, selectivity for actinide or other metal ions, the ability to recover a metal once it is bound to the peptoid, and whether the overall peptoid should be hydrophobic or hydrophilic. Unlike siderophores, peptoid-based chelating ligands of the present disclosure are not readily hydrolyzed under physiological conditions. Therefore, peptoid-based chelating ligands may be, for example, used to treat actinide (e.g., iron and lead) poisoning in vivo. Moreover, peptoid-based chelating ligands of the present disclosure may be used for medical imaging, chelation therapy, drug delivery, and separation technologies, for example.
ANTIBACTERIAL SIDEROMYCINS
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, (2016/03/13)
A compound, comprising: an Fe(III)-binding and/or Fe(III)-bound siderophore; one or more optional linker covalently bound to the siderophore; and daptomycin covalently bound to the linker, or, if no linker is present, then to the siderophore; or pharmaceu
