Methyl 3-(8-chloro-5-methoxy-4-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)propanoate

Base Information

Chemical Name:Methyl 3-(8-chloro-5-methoxy-4-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)propanoate
CAS No.:792-43-8
Molecular Formula:C₁₅H₁₇ClO₄
Molecular Weight:296.751
Hs Code.:
NSC Number:71281
DSSTox Substance ID:DTXSID40290827

Synonyms:792-43-8;NSC71281;methyl 3-(8-chloro-5-methoxy-4-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)propanoate;DTXSID40290827;NSC-71281;methyl 3-(8-chloro-5-methoxy-4-oxo-1,2,3,4-tetrahydro-2-naphthalenyl)propanoate

Suppliers and Price of Methyl 3-(8-chloro-5-methoxy-4-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Methyl 3-(8-chloro-5-methoxy-4-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)propanoate

Chemical Property:

Vapor Pressure:1.03E-07mmHg at 25°C
Boiling Point:433.4°Cat760mmHg
Flash Point:171°C
Density:1.222g/cm³
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:296.0815367
Heavy Atom Count:20
Complexity:371

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C2C(=C(C=C1)Cl)CC(CC2=O)CCC(=O)OC

Technology Process of Methyl 3-(8-chloro-5-methoxy-4-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)propanoate

There total 8 articles about Methyl 3-(8-chloro-5-methoxy-4-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5368-81-0
methyl 3-methoxybenzoate

: 792-43-8
2-(2-Carbomethoxyethyl)-5-methoxy-8-chlor-4-tetralon

Guidance literature:: Multi-step reaction with 7 steps

1: NaH

2: NaH

3: aq. H₂SO₄, AcOH / Heating

4: H₂SO₄

5: (i) H₂, Pd-C, (ii) /BRN= 1098229/, H₂SO₄

6: (i) aq. NaOH, (ii) Cl₂, I₂, AcOH, (iii) HF

7: H₂SO₄

With sulfuric acid; sodium hydride; acetic acid;
DOI:10.1021/ja01004a041

Reference yield:

: 795-17-5
β-(3-Methoxybenzyl)-adipinsaeure-dimethylester

: 792-43-8
2-(2-Carbomethoxyethyl)-5-methoxy-8-chlor-4-tetralon

Guidance literature:: Multi-step reaction with 2 steps

1: (i) aq. NaOH, (ii) Cl₂, I₂, AcOH, (iii) HF

2: H₂SO₄

With sulfuric acid;
DOI:10.1021/ja01004a041

Reference yield:

: 17797-68-1
β-(3-Methoxybenzoyl)-adipinsaeure

: 792-43-8
2-(2-Carbomethoxyethyl)-5-methoxy-8-chlor-4-tetralon

Guidance literature:: Multi-step reaction with 4 steps

1: H₂SO₄

2: (i) H₂, Pd-C, (ii) /BRN= 1098229/, H₂SO₄

3: (i) aq. NaOH, (ii) Cl₂, I₂, AcOH, (iii) HF

4: H₂SO₄

With sulfuric acid;
DOI:10.1021/ja01004a041