Methyl 2-[4-(diethylsulfamoyl)phenoxy]acetate

Base Information

Chemical Name:Methyl 2-[4-(diethylsulfamoyl)phenoxy]acetate
CAS No.:114617-87-7
Molecular Formula:C13H19NO5S
Molecular Weight:301.364
Hs Code.:
DSSTox Substance ID:DTXSID30358405
Wikidata:Q82138933

Synonyms:114617-87-7;methyl 2-[4-(diethylsulfamoyl)phenoxy]acetate;ST4109430;DTXSID30358405;STK727733;AKOS001739229;methyl [4-(diethylsulfamoyl)phenoxy]acetate;methyl {4-[(diethylamino)sulfonyl]phenoxy}acetate;SR-01000265654;SR-01000265654-1

Suppliers and Price of Methyl 2-[4-(diethylsulfamoyl)phenoxy]acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Methyl 2-[4-(diethylsulfamoyl)phenoxy]acetate

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:8
Exact Mass:301.09839388
Heavy Atom Count:20
Complexity:392

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)S(=O)(=O)C1=CC=C(C=C1)OCC(=O)OC

Technology Process of Methyl 2-[4-(diethylsulfamoyl)phenoxy]acetate

There total 4 articles about Methyl 2-[4-(diethylsulfamoyl)phenoxy]acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 56077-78-2
4-(methyloxycarbonylmethylenoxy)benzenesulfonyl chloride

: 109-89-7
diethylamine

: 114617-87-7
methyl 2-(4-(N,N-diethylsulfamoyl) phenoxy)acetate

Guidance literature:

Reference yield:

: sodium 4-(2-methoxy-2-oxoethoxy)benzenesulfonate

: 114617-87-7
methyl 2-(4-(N,N-diethylsulfamoyl) phenoxy)acetate

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride; N,N-dimethyl-formamide / 4 h / Reflux

2: triethylamine; dmap / dichloromethane / 24 h / 20 °C

With dmap; thionyl chloride; triethylamine; N,N-dimethyl-formamide; In dichloromethane;
DOI:10.1016/j.bmcl.2018.08.030

Reference yield:

: 825-90-1
sodium p-hydroxybenzenesulfonate

: 114617-87-7
methyl 2-(4-(N,N-diethylsulfamoyl) phenoxy)acetate

Guidance literature:: Multi-step reaction with 3 steps

1: sodium carbonate / methanol / Reflux

2: thionyl chloride; N,N-dimethyl-formamide / 4 h / Reflux

3: triethylamine; dmap / dichloromethane / 24 h / 20 °C

With dmap; thionyl chloride; sodium carbonate; triethylamine; N,N-dimethyl-formamide; In methanol; dichloromethane;
DOI:10.1016/j.bmcl.2018.08.030