56077-78-2

Basic information

• Product Name: (4-Chlorosulfonylphenoxy)acetic acid methyl ester
• Synonyms: (4-Chlorosulfonylphenoxy)acetic acid methyl ester;Methyl 2-[4-(chlorosulfonyl)phenoxy]acetate;Acetic acid,2-[4-(chlorosulfonyl)phenoxy]-,methyl ester
• CAS NO: 56077-78-2
• Molecular Formula: C₉H₉ClO₅S
• Molecular Weight: 264.68
• Product Categories: Heterocycles
• Mol File: 56077-78-2.mol
• Article Data: 6

Chemical Properties

• Melting Point: 63-64 ºC
• Boiling Point: 381.487 °C at 760 mmHg
• Flash Point: 184.517 °C
• Appearance: /
• Density: 1.418
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.533
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (4-Chlorosulfonylphenoxy)acetic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4-Chlorosulfonylphenoxy)acetic acid methyl ester(56077-78-2)
• EPA Substance Registry System: (4-Chlorosulfonylphenoxy)acetic acid methyl ester(56077-78-2)

Safety Data

• Hazardous Substances Data: 56077-78-2(Hazardous Substances Data)

Usage

General Description

"(4-Chlorosulfonylphenoxy)acetic acid methyl ester" is a chemical compound deriving from acetic acid methyl ester, featuring a phenoxy structure substituted with a chlorosulfonyl group at the 4 position. This group features a sulphur atom bound to a chlorine atom, conferring the molecule distinct reactivity properties. It is a synthetic compound, produced in laboratory settings, and known for its application in chemical research, particularly in generating derivatives for studies in organic synthesis. Its properties, toxicity, environmental impact and specific suitable uses usually depend on the specific compound it is a part of.

InChI:InChI=1/C9H9ClO5S/c1-14-9(11)6-15-7-2-4-8(5-3-7)16(10,12)13/h2-5H,6H2,1H3

Upstream product

• 825-90-1 sodium p-hydroxybenzenesulfonate 
• 67-56-1 methanol 
• 2065-23-8 methyl 2-phenoxyacetate 

Downstream Products

• 99987-21-0 (4-dimethylsulfamoyl-phenoxy)-acetic acid methyl ester 
• 373359-61-6 {4-[4-(4-oxopiperidin-1-yl)phenylsulfamoyl]phenoxy}acetic acid methyl ester 
• 651729-80-5 [4-(3-methoxy-phenylsulfamoyl)-phenoxy]acetic acid methyl ester 
• 651729-58-7 methyl 2-(3-([(4-methoxy-2-nitrophenyl)amino]sulfonyl)phenoxy)acetate 
• 519182-99-1 {4-[6-methoxy-2-(4-methoxy-3,5-dimethyl-2-pyridinyl)methylsulfinylbenzimidazole-1-sulfonyl]phenoxy}acetic acid methyl ester 
• 1354949-07-7 C₂₂H₃₂N₂O₆S 
• 91637-10-4 N,N-diethyl-4-(2-hydrazinyl-2-oxoethoxy)benzenesulfonamide 
• 29149-55-1 methyl 2-(4-(N-ethylsulfamoyl)phenoxy)acetate 
• 93009-61-1 methyl 2-(4-(N-p-tolylsulfamoyl)phenoxy)acetate 
• 1198399-89-1 1-[N-[4-(methyloxycarbonylmethylenoxy)benzenesulfonyl]-2-aminoethyl]-1,4,7,10-tetraazacyclododecane-4,7,10-triacetic acid tri(1,1-dimethylethyl ester) 

Relevant articles and documents

Synthesis method and application of two sulfonyl pyrrolidine P-CABs

The invention discloses a synthesis method and application of two sulfonyl pyrrolidine P-CABs. The general structural formula (I) of the sulfonyl pyrrolidine is shown in the specification. The sulfonyl pyrrolidine has excellent gastric acid secretion inhibition effect. The synthesis method has the advantages of fewer process steps and easy availability of raw materials, and is suitable for industrial production.

Poly-β-cyclodextrin based platform for pH mapping via a ratiometric 19F/1H MRI method

The in vitro validation of a new pH mapping MRI method based on a supramolecular poly-β-cyclodextrin-19F-Gd adduct is reported.

Process for preparing isomerically pure prodrugs of proton pump inhibitors

Synthetic methods for preparing isomerically pure N-arylsulfonyl derivatives of proton pump inhibitors which include a substituted benzimidazole nucleus are shown by the synthetic schemes and experimental description.