5-Chloro-2-(methoxymethoxy)benzaldehyde

Base Information

Chemical Name:5-Chloro-2-(methoxymethoxy)benzaldehyde
CAS No.:115560-38-8
Molecular Formula:C9H9ClO3
Molecular Weight:200.622
Hs Code.:
DSSTox Substance ID:DTXSID90554022
Wikidata:Q82434816

Synonyms:5-Chloro-2-(methoxymethoxy)benzaldehyde;115560-38-8;Benzaldehyde, 5-chloro-2-(methoxymethoxy)-;5-chloro-2-methoxymethoxybenzaldehyde;SCHEMBL4039108;DTXSID90554022;AFVFFHSQPVBSIY-UHFFFAOYSA-N;MFCD21195358;AKOS014699907;CS-0190611;E92070;A1-05008

Suppliers and Price of 5-Chloro-2-(methoxymethoxy)benzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 5-Chloro-2-(methoxymethoxy)benzaldehyde

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:200.0240218
Heavy Atom Count:13
Complexity:163

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COCOC1=C(C=C(C=C1)Cl)C=O

Technology Process of 5-Chloro-2-(methoxymethoxy)benzaldehyde

There total 4 articles about 5-Chloro-2-(methoxymethoxy)benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.7%

: 107-30-2
chloromethyl methyl ether

: 635-93-8
5-chlorosalicyclaldehyde

: 115560-38-8
2-(methoxymethoxy)-5-chlorobenzaldehyde

Guidance literature:: 5-chlorosalicyclaldehyde; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃;

chloromethyl methyl ether; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 2h;
DOI:10.1016/j.ejmech.2012.06.034

Reference yield:

: 106-48-9,82344-39-6
4-chloro-phenol

: 115560-38-8
2-(methoxymethoxy)-5-chlorobenzaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / p-toluenesulfonic acid, 4-A sieves / CH₂Cl₂ / 48 h / Heating

2: 1.) n-butyllithium, TMEDA / 1.) ether, hexane, -20 deg C, 1 h, 2.) 1 h

With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; 4 A molecular sieve; toluene-4-sulfonic acid; In dichloromethane;
DOI:10.1021/jo00252a011

Reference yield:

: 826-26-6
1-chloro-4-(methoxymethoxy)benzene

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 115560-38-8
2-(methoxymethoxy)-5-chlorobenzaldehyde

Guidance literature:: With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; Yield given. Multistep reaction; 1.) ether, hexane, -20 deg C, 1 h, 2.) 1 h;
DOI:10.1021/jo00252a011