4-Amino-3,5-dichloro-6-fluoro-2-pyridone

Base Information

• Chemical Name: 4-Amino-3,5-dichloro-6-fluoro-2-pyridone
• CAS No.: 94133-62-7
• Molecular Formula: C5H3 Cl2 F N2 O
• Molecular Weight: 196.996
• Hs Code.: 2933399090
• European Community (EC) Number: 302-724-5
• UNII: NJ77HH93E8
• DSSTox Substance ID: DTXSID70240673
• Nikkaji Number: J304.918C
• Wikidata: Q83123671
• Mol file: 94133-62-7.mol

Synonyms:94133-62-7;4-Amino-3,5-dichloro-6-fluoropyridin-2(1H)-one;4-Amino-3,5-dichloro-6-fluoro-2-pyridone;4-amino-3,5-dichloro-6-fluoro-1H-pyridin-2-one;Fluroxypyr-2-hydroxy;4-Amino-3,5-dichloro-6-fluoro-2-hydroxypyridine;4-amino-3,5-dichloro-6-fluoropyridin-2-ol;EINECS 302-724-5;C5H3Cl2FN2O;4-Amino-3,5-dichloro-6-fluoro-2(1H)-pyridinone;NJ77HH93E8;Fluroxypyr-2-hydroxy 100 microg/mL in Acetonitrile;Pyridinol (DCP);fluroxypyr-meptyl TP1;UNII-NJ77HH93E8;2-hydroxy-3,5-dichloro-4-amino-6-fluoropyridine;SCHEMBL8409269;C5-H3-Cl2-F-N2-O;DTXSID70240673;MFCD09751333;AKOS006327327;DS-5144;4-amino-3,5-dichloro-6-fluoro-2-pyridinol;CS-0132536;A26084;C77242;2(1H)-Pyridinone, 4-amino-3,5-dichloro-6-fluoro-;4-amino-3,5-dichloro-6-fluoro-1,2-dihydropyridin-2-one;4-Amino-3,5-dichloro-6-difluoro-2(1H)-pyridinone

Chemical Property of 4-Amino-3,5-dichloro-6-fluoro-2-pyridone

Chemical Property:

• Vapor Pressure: 8mmHg at 25°C
• Boiling Point: 134.7°Cat760mmHg
• PKA: 3.54±0.20(Predicted)
• Flash Point: 35.3°C
• PSA: 58.88000
• Density: 1.69g/cm³
• LogP: 1.98420
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 195.9606463
• Heavy Atom Count: 11
• Complexity: 284

Purity/Quality:

97% ^*data from raw suppliers

4-Amino-3,5-dichloro-6-fluoropyridin-2(1H)-one 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1(=C(C(=O)NC(=C1Cl)F)Cl)N

Technology Process of 4-Amino-3,5-dichloro-6-fluoro-2-pyridone

There total 3 articles about 4-Amino-3,5-dichloro-6-fluoro-2-pyridone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.5%

4-amino-3,5-dichloro-2,6-difluoropyridine (2840-00-8) → 4-amino-3,5-dichloro-6-fluoro-2-pyridinol (94133-62-7)

Guidance literature:

With sodium hydroxide; In N,N-dimethyl acetamide; at 100 ℃; for 3h; Reagent/catalyst; Temperature;

Reference yield:

2,3,4,5,6-pentachloropyridine (2176-62-7) → 4-amino-3,5-dichloro-6-fluoro-2-pyridinol (94133-62-7)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium fluoride; N-benzyl-N,N,N-triethylammonium chloride / N,N-dimethyl acetamide / 3 h / 120 °C / Molecular sieve

2: ammonium hydroxide / N,N-dimethyl acetamide / 10 °C

3: sodium hydroxide / N,N-dimethyl acetamide / 3 h / 100 °C

With potassium fluoride; ammonium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; sodium hydroxide; In N,N-dimethyl acetamide;

Reference yield:

3,5-dichloro-2,4,6-trifluoropyridine (1737-93-5,259875-95-1) → 4-amino-3,5-dichloro-6-fluoro-2-pyridinol (94133-62-7)

Guidance literature:

Multi-step reaction with 2 steps

1: ammonium hydroxide / N,N-dimethyl acetamide / 10 °C

2: sodium hydroxide / N,N-dimethyl acetamide / 3 h / 100 °C

With ammonium hydroxide; sodium hydroxide; In N,N-dimethyl acetamide;

upstream raw materials:

2,3,4,5,6-pentachloropyridine

3,5-dichloro-2,4,6-trifluoropyridine

4-amino-3,5-dichloro-2,6-difluoropyridine

Downstream raw materials:

2-[(4-amino-3,5-dichloro-6-fluoro-2-pyridinyl)oxy]acetic acid 1-methylheptyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 94133-62-7 4-amino-3,5-dichloro-6-fluoro-2-pyridone

Send

Send

Metric Ton KG G Pound L ML

Send

Send