Guanidine, N-cyclohexyl-N'-(4,5-dihydro-2-thiazolyl)-N''-(2-methyl-4-quinolinyl)-

Base Information

Chemical Name:Guanidine, N-cyclohexyl-N'-(4,5-dihydro-2-thiazolyl)-N''-(2-methyl-4-quinolinyl)-
CAS No.:72042-08-1
Molecular Formula:C₂₀H₂₅N₅S
Molecular Weight:367.518
Hs Code.:
DSSTox Substance ID:DTXSID20222368
Mol file:72042-08-1.mol

Synonyms:72042-08-1;BRN 5614490;Guanidine, N-cyclohexyl-N'-(4,5-dihydro-2-thiazolyl)-N''-(2-methyl-4-quinolinyl)-;Guanidine, 1-cyclohexyl-2-(2-methyl-4-quinolyl)-3-(2-thiazolinyl)-;N-Cyclohexyl-N'-(4,5-dihydro-2-thiazolyl)-N''-(2-methyl-4-quinolinyl)guanidine;1-Cyclohexyl-3-(4,5-dihydrothiazol-2-yl)-2-(2-methylquinolin-4-yl)guanidine;DTXSID20222368;LS-73502

Suppliers and Price of Guanidine, N-cyclohexyl-N'-(4,5-dihydro-2-thiazolyl)-N''-(2-methyl-4-quinolinyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Guanidine, N-cyclohexyl-N'-(4,5-dihydro-2-thiazolyl)-N''-(2-methyl-4-quinolinyl)-

Chemical Property:

Vapor Pressure:1.03E-11mmHg at 25°C
Boiling Point:539.7°C at 760 mmHg
Flash Point:280.2°C
PSA：90.20000
Density:1.32g/cm³
LogP:3.58460
XLogP3:3.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:367.18306699
Heavy Atom Count:26
Complexity:528

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC2=CC=CC=C2C(=C1)NC(=NC3CCCCC3)NC4=NCCS4

Technology Process of Guanidine, N-cyclohexyl-N'-(4,5-dihydro-2-thiazolyl)-N''-(2-methyl-4-quinolinyl)-

There total 3 articles about Guanidine, N-cyclohexyl-N'-(4,5-dihydro-2-thiazolyl)-N''-(2-methyl-4-quinolinyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 1779-81-3
4,5-Dihydro-thiazol-2-ylamin

: 71079-18-0
N¹-cyclohexyl-N²-(2-methyl-4-quinolyl)carbodiimide

: 72042-08-1
N-cyclohexyl-N'-(4,5-dihydro-thiazol-2-yl)-N''-(2-methyl-quinolin-4-yl)-guanidine

Guidance literature:: for 0.5h; Heating;
DOI:10.1021/jm00175a004

Reference yield:

: 71070-70-7
N-cyclohexyl-N'-4-(2-methylquinolyl)urea

: 72042-08-1
N-cyclohexyl-N'-(4,5-dihydro-thiazol-2-yl)-N''-(2-methyl-quinolin-4-yl)-guanidine

Guidance literature:: Multi-step reaction with 2 steps

1: Ph₃P, Et₃N / CCl₄; CH₂Cl₂ / 2 h / Heating

2: 62 percent / 0.5 h / Heating

With triethylamine; triphenylphosphine; In tetrachloromethane; dichloromethane;
DOI:10.1021/jm00175a004