L-Phenylalanine, N-[N-[N-[N-[N-[(1,1-dimethylethoxy)carbonyl]-L-a-aspartyl]glycyl]-L-phen ylalanyl]-L-phenylalanyl]-, 1-ethyl 4-(phenylmethyl) ester

Base Information

Chemical Name:L-Phenylalanine, N-[N-[N-[N-[N-[(1,1-dimethylethoxy)carbonyl]-L-a-aspartyl]glycyl]-L-phen ylalanyl]-L-phenylalanyl]-, 1-ethyl 4-(phenylmethyl) ester
CAS No.:116064-62-1
Molecular Formula:C₄₇H₅₅N₅O₁₀
Molecular Weight:849.981
Hs Code.:

L-Phenylalanine,
N-[N-[N-[N-[N-[(1,1-dimethylethoxy)carbonyl]-L-a-aspartyl]glycyl]-L-phen
ylalanyl]-L-phenylalanyl]-, 1-ethyl 4-(phenylmethyl) ester

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Chemical Property of L-Phenylalanine, N-[N-[N-[N-[N-[(1,1-dimethylethoxy)carbonyl]-L-a-aspartyl]glycyl]-L-phen ylalanyl]-L-phenylalanyl]-, 1-ethyl 4-(phenylmethyl) ester

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Technology Process of L-Phenylalanine, N-[N-[N-[N-[N-[(1,1-dimethylethoxy)carbonyl]-L-a-aspartyl]glycyl]-L-phen ylalanyl]-L-phenylalanyl]-, 1-ethyl 4-(phenylmethyl) ester

There total 2 articles about L-Phenylalanine, N-[N-[N-[N-[N-[(1,1-dimethylethoxy)carbonyl]-L-a-aspartyl]glycyl]-L-phen ylalanyl]-L-phenylalanyl]-, 1-ethyl 4-(phenylmethyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 74973-88-9
Z-Phe-Phe-Phe-OEt

: 116064-62-1
Boc-Asp(OBzl)-Gly-Phe-Phe-Phe-OEt

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) 25percent HBr, AcOH; 2.) triethylamine / 1.)anisol 1 h; 2.) THF, 3 day

2: 1.) 25percent HBr, AcOH; 2.) triethylamine / 1.) anisol, 1 h; 2.) DMF, 3 day

With hydrogen bromide; acetic acid; triethylamine;

Reference yield:

: 26048-69-1
(S)-2-tert-Butoxycarbonylamino-succinic acid 4-benzyl ester 1-(4-nitro-phenyl) ester

: 116064-60-9
(S)-2-{(S)-2-[(S)-2-(2-Benzyloxycarbonylamino-acetylamino)-3-phenyl-propionylamino]-3-phenyl-propionylamino}-3-phenyl-propionic acid ethyl ester

: 116064-62-1
Boc-Asp(OBzl)-Gly-Phe-Phe-Phe-OEt

Guidance literature:: With hydrogen bromide; acetic acid; triethylamine; Yield given. Multistep reaction; 1.) anisol, 1 h; 2.) DMF, 3 day;

Reference yield:

: 116064-62-1
Boc-Asp(OBzl)-Gly-Phe-Phe-Phe-OEt

: Lys-Asp-Gly-Phe-Phe-Phe

Guidance literature:: Multi-step reaction with 2 steps

2: 1.) 2n KOH; 2.) 25percent HBr, AcOH / 1.) DMF; 2.) anisol

With potassium hydroxide; hydrogen bromide; acetic acid;