26048-69-1Relevant articles and documents
α-AMINOACYL DERIVATIVES OF α,ω-DIAMINOPOLY(OXYETHYLENE)
Masar, Bohumil,Schmidt, Pavel,Pivcova, Hana,Cefelin, Pavel
, p. 1922 - 1927 (2007/10/02)
By reacting p-nitrophenyl esters of L-α-amino acids with α-(3-aminopropyl)-ω-(aminomethyl)poly(oxyethylene), diamides having the structure 2M'x were prepared, X being the protective group Boc or Z, R being residues of glutamic and aspartic acid, phenylalanine and tyrosine, and M'x being the poly(oxyethylene) chain with the (-CH2)3- and -CH2- endgroups.The diamides were characterized by IR and 1H NMR spectroscopy and thin-layer chromatography.After complete removal of tert-butyloxycarbonyl groups from diamides (X=Boc), deprotected α-aminoacyl derivatives were characterized as trifluoroacetic acid salts.