5-(naphthalen-1-yl)-1,3,4-oxadiazole-2-thiol

Base Information

Chemical Name:5-(naphthalen-1-yl)-1,3,4-oxadiazole-2-thiol
CAS No.:116082-89-4
Molecular Formula:C12H8N2OS
Molecular Weight:228.274
Hs Code.:
Mol file:116082-89-4.mol

Synonyms:5-[1]Naphthyl-3H-[1,3,4]oxadiazol-2-thion;5-Naphthalen-1-yl-3H-[1,3,4]oxadiazole-2-thione;

Suppliers and Price of 5-(naphthalen-1-yl)-1,3,4-oxadiazole-2-thiol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-(Naphthalen-1-yl)-1,3,4-oxadiazole-2-thiol
50mg
$ 90.00

AK Scientific
5-(Naphthalen-1-yl)-1,3,4-oxadiazole-2-thiol
5g
$ 1494.00

AK Scientific
5-(Naphthalen-1-yl)-1,3,4-oxadiazole-2-thiol
500mg
$ 445.00

Total 2 raw suppliers

Chemical Property of 5-(naphthalen-1-yl)-1,3,4-oxadiazole-2-thiol

Chemical Property:

PSA：73.91000
LogP:3.55240

Purity/Quality:

99% ^*data from raw suppliers

5-(Naphthalen-1-yl)-1,3,4-oxadiazole-2-thiol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-(naphthalen-1-yl)-1,3,4-oxadiazole-2-thiol

There total 10 articles about 5-(naphthalen-1-yl)-1,3,4-oxadiazole-2-thiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 75-15-0,12122-00-8
carbon disulfide

: 43038-45-5
1-naphthohydrazide

: 116082-89-4
5-(naphthalen-1-yl)-1,3,4-oxadiazole-2-thiol

Guidance literature:: 1-naphthohydrazide; With potassium hydroxide; In methanol; at 20 ℃; for 0.5h;

carbon disulfide; In methanol; at 70 ℃; for 24h; Reflux;
DOI:10.1016/j.tetlet.2020.152668

Reference yield:

: 75-15-0,12122-00-8
carbon disulfide

: 43038-45-5
1-naphthohydrazide

: 116082-89-4
5-[1]naphthyl-3H-[1,3,4]oxadiazole-2-thione

Guidance literature:: With potassium hydroxide; In ethanol; at 80 ℃; for 12h;
DOI:10.1016/j.bmc.2010.04.021

Reference yield:

: 86-55-5
1-naphthalenecarboxylic acid

: 116082-89-4
5-(naphthalen-1-yl)-1,3,4-oxadiazole-2-thiol

Guidance literature:: Multi-step reaction with 3 steps

1.1: sulfuric acid / Reflux

2.1: hydrazine hydrate / ethanol / Reflux

3.1: potassium hydroxide / ethanol / 24 h / Reflux

3.2: pH 5 - 6

With sulfuric acid; hydrazine hydrate; potassium hydroxide; In ethanol;
DOI:10.1016/j.bmc.2012.03.061