Technology Process of 7-Octen-3-ol, 1-(phenylmethoxy)-, (S)-
There total 8 articles about 7-Octen-3-ol, 1-(phenylmethoxy)-, (S)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
1-bromo-4-butene;
With
magnesium; ethylene dibromide;
In
tetrahydrofuran;
at 20 ℃;
for 1h;
With
lithium tetrachlorocuprate;
In
tetrahydrofuran;
at -78 ℃;
for 1h;
(2R)-2-(2-benzyloxyethyl)oxirane;
In
tetrahydrofuran;
at -78 - 20 ℃;
Further stages.;
DOI:10.1055/s-2006-942363
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: Ph3P; DIAD / benzene / 20 h / Heating
2.1: Mg; CH2BrCH2Br / tetrahydrofuran / 1 h / 20 °C
2.2: LiCuCl4 / tetrahydrofuran / 1 h / -78 °C
2.3: 90 percent / tetrahydrofuran / -78 - 20 °C
With
di-isopropyl azodicarboxylate; magnesium; ethylene dibromide; triphenylphosphine;
In
tetrahydrofuran; benzene;
1.1: Mitsunobu reaction;
DOI:10.1055/s-2006-942363
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: 90 percent / NaH / tetrahydrofuran
2.1: MCPBA / CH2Cl2
3.1: 43 percent / (R,R)-salen-Co(III)-OAc complex; H2O / 5 h / 20 °C
4.1: Ph3P; DIAD / benzene / 20 h / Heating
5.1: Mg; CH2BrCH2Br / tetrahydrofuran / 1 h / 20 °C
5.2: LiCuCl4 / tetrahydrofuran / 1 h / -78 °C
5.3: 90 percent / tetrahydrofuran / -78 - 20 °C
With
di-isopropyl azodicarboxylate; water; sodium hydride; magnesium; ethylene dibromide; 3-chloro-benzenecarboperoxoic acid; triphenylphosphine;
In
tetrahydrofuran; dichloromethane; benzene;
3.1: Jacobsen's hydrolytic kinetic resolution / 4.1: Mitsunobu reaction;
DOI:10.1055/s-2006-942363
