Phenol, 3-bromo-4-methoxy-, acetate

Base Information

• Chemical Name: Phenol, 3-bromo-4-methoxy-, acetate
• CAS No.: 124764-37-0
• Molecular Formula: C9H9BrO3
• Molecular Weight: 245.073
• Mol file: 124764-37-0.mol

Synonyms:Acetic acid 3-bromo-4-methoxy-phenyl ester;.acetic acid 3-bromo-4-methoxyphenyl ester;

Chemical Property of Phenol, 3-bromo-4-methoxy-, acetate

Chemical Property:

• PSA: 35.53000
• LogP: 2.38300

Purity/Quality:

95% ^*data from raw suppliers

3-Bromo-4-methoxyphenolAcetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Phenol, 3-bromo-4-methoxy-, acetate

There total 2 articles about Phenol, 3-bromo-4-methoxy-, acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-methoxyphenyl acetate (1200-06-2) → 3-bromo-4-methoxyphenyl acetate (124764-37-0)

Guidance literature:

4-methoxyphenyl acetate; With N-Bromosuccinimide; In acetonitrile; at 20 ℃; for 24h;

With N-Bromosuccinimide; for 24h;

Reference yield:

4-methoxy-phenol (150-76-5) → 3-bromo-4-methoxyphenyl acetate (124764-37-0)

Guidance literature:

Multi-step reaction with 2 steps

1: dmap / tetrahydrofuran / 2 h / 20 °C / Inert atmosphere

2: acetic acid; sodium acetate; bromine / 0 - 20 °C / Inert atmosphere

With dmap; bromine; sodium acetate; acetic acid; In tetrahydrofuran;

DOI:10.1021/ol401787n

Reference yield: 98.04%

3-bromo-4-methoxyphenyl acetate (124764-37-0) → 3-bromo-4-methoxy-phenol (17332-12-6)

Guidance literature:

3-bromo-4-methoxyphenyl acetate; With water; potassium hydroxide; In methanol; at 20 ℃; for 0.5h;

With hydrogenchloride; In water; Acidic aqueous solution;

upstream raw materials:

4-methoxyphenyl acetate

4-methoxy-phenol

Downstream raw materials:

3-bromo-4-methoxy-phenol

acetic acid 4-methoxy-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl ester

2-allyl-5-bromo-4-methoxyphenol

Refernces

• 1、 -. "A synthesizing methyl emulsion method of alkali". Paragraph 0045; 0046. . Retrieved 2016/10/10.
• 2、 -. "AZETIDINE DERIVATIVES". Page/Page column 36; 37. . Retrieved 2009/10/22.