N-(2,3-Dimethylphenyl)acetamide

Base Information

• Chemical Name: N-(2,3-Dimethylphenyl)acetamide
• CAS No.: 134-98-5
• Molecular Formula: C10H13 N O
• Molecular Weight: 163.219
• Hs Code.: 2924299090
• NSC Number: 186201
• UNII: 5AQA6T12HY
• DSSTox Substance ID: DTXSID60158455
• Nikkaji Number: J55.067A
• Wikidata: Q83026717
• Mol file: 134-98-5.mol

Synonyms:2,3-didehydro-5-O-mycaminosyl-23-O-acetyltylonolide;2,3-DMA

Chemical Property of N-(2,3-Dimethylphenyl)acetamide

Chemical Property:

• Vapor Pressure: 0.0012mmHg at 25°C
• Boiling Point: 299.3 °C at 760 mmHg
• Flash Point: 173.8 °C
• PSA: 29.10000
• Density: 1.052 g/cm³
• LogP: 2.33480
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 163.099714038
• Heavy Atom Count: 12
• Complexity: 167

Purity/Quality:

99% ^*data from raw suppliers

N-(2,3-Dimethylphenyl)acetamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C(=CC=C1)NC(=O)C)C

Technology Process of N-(2,3-Dimethylphenyl)acetamide

There total 8 articles about N-(2,3-Dimethylphenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

acetic anhydride (108-24-7) + 2,3-Dimethylaniline (87-59-2) → N-(2,3-dimethylphenyl)acetamide (134-98-5)

Guidance literature:

With Ni₂B-Cu₂O nanocomposite; In neat (no solvent); at 40 ℃; for 0.0166667h; Reagent/catalyst;

DOI:10.1007/s11164-018-3559-x

Reference yield: 94.0%

2,3-dimethylnitrobenzene (83-41-0) + acetic anhydride (108-24-7) → N-(2,3-dimethylphenyl)acetamide (134-98-5)

Guidance literature:

2,3-dimethylnitrobenzene; With sodium tetrahydroborate; In water; at 60 - 70 ℃; Green chemistry;

acetic anhydride; In water; at 60 - 70 ℃; Green chemistry;

DOI:10.1007/s13738-018-1469-x

Reference yield: 93.0%

acetyl chloride (75-36-5) + 2,3-Dimethylaniline (87-59-2) → N-(2,3-dimethylphenyl)acetamide (134-98-5)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃;

upstream raw materials:

acetic anhydride

2,3-Dimethylaniline

acetic acid

acetyl chloride

Downstream raw materials:

2,4-dimethyl-1H-indole

2,3-dimethyl-6-nitroaniline

4'-Chlor-2',3'-dimethyl-acetanilid

acetic acid-(6-chloro-2,3-dimethyl-anilide)