2-Amino-4-azido-3,5,6-trifluorobenzoic acid

Base Information

Chemical Name:2-Amino-4-azido-3,5,6-trifluorobenzoic acid
CAS No.:126695-67-8
Molecular Formula:C7H3F3N4O2
Molecular Weight:232.122
Hs Code.:
DSSTox Substance ID:DTXSID40562511
Nikkaji Number:J323.738I
Wikidata:Q82446705
Mol file:126695-67-8.mol

Synonyms:2-Amino-4-azido-3,5,6-trifluorobenzoic acid;126695-67-8;DTXSID40562511

Suppliers and Price of 2-Amino-4-azido-3,5,6-trifluorobenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2-Amino-4-azido-3,5,6-trifluorobenzoic acid

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:2
Exact Mass:232.02080984
Heavy Atom Count:16
Complexity:336

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1(=C(C(=C(C(=C1F)F)N=[N+]=[N-])F)N)C(=O)O

Technology Process of 2-Amino-4-azido-3,5,6-trifluorobenzoic acid

There total 5 articles about 2-Amino-4-azido-3,5,6-trifluorobenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 126695-64-5
methyl 2-amino-4-azido-3,5,6-trifluorobenzoate

: 126695-67-8
2-amino-4-azido-3,5,6-trifluorobenzoic acid

Guidance literature:: With sodium hydroxide; In methanol; water;
DOI:10.1021/jo00298a048

Reference yield:

: 122590-80-1
2-amino-4-azido-3,5,6-trifluorobenzamide

: 126695-67-8
2-amino-4-azido-3,5,6-trifluorobenzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: amberlyst 15 resin / 70 h / Heating

2: NaOH / H₂O; methanol / 2 h / 25 °C

With sodium hydroxide; Amberlyst 15 resin; In methanol; water;
DOI:10.1016/S0040-4039(01)80580-3

Reference yield:

: 773-82-0
Pentafluorobenzonitrile

: 126695-67-8
2-amino-4-azido-3,5,6-trifluorobenzoic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 18 percent / H₂O₂, (n-C₄H₉)4NHSO₄, 20percent aq. NaOH / CH₂Cl₂ / 40 h / 25 °C

2: 49 percent / NH₃ / dimethylsulfoxide / 120 h / 75 °C

3: 88 percent / Amberlyst 15 / 70 h / Heating

4: 98 percent / 20percent aq. NaOH / H₂O; methanol

With sodium hydroxide; Amberlyst 15; ammonia; dihydrogen peroxide; tetra(n-butyl)ammonium hydrogensulfate; In methanol; dichloromethane; water; dimethyl sulfoxide;
DOI:10.1021/jo00298a048