Technology Process of 4-azido-2-nitro-3,5,6-trifluorobenzoic acid
There total 6 articles about 4-azido-2-nitro-3,5,6-trifluorobenzoic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
trifluoroacetyl peroxide;
In
dichloromethane;
Heating;
DOI:10.1021/jo00298a048
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 18 percent / H2O2, (n-C4H9)4NHSO4, 20percent aq. NaOH / CH2Cl2 / 40 h / 25 °C
2: 49 percent / NH3 / dimethylsulfoxide / 120 h / 75 °C
3: 88 percent / Amberlyst 15 / 70 h / Heating
4: 98 percent / 20percent aq. NaOH / H2O; methanol
5: 72 percent / CF3CO3H / CH2Cl2 / Heating
With
sodium hydroxide; Amberlyst 15; trifluoroacetyl peroxide; ammonia; dihydrogen peroxide; tetra(n-butyl)ammonium hydrogensulfate;
In
methanol; dichloromethane; water; dimethyl sulfoxide;
DOI:10.1021/jo00298a048
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 83 percent / NaN3 / acetone; H2O / 8 h / Heating
2: 49 percent / NH3 / dimethylsulfoxide / 120 h / 75 °C
3: 88 percent / Amberlyst 15 / 70 h / Heating
4: 98 percent / 20percent aq. NaOH / H2O; methanol
5: 72 percent / CF3CO3H / CH2Cl2 / Heating
With
sodium hydroxide; sodium azide; Amberlyst 15; trifluoroacetyl peroxide; ammonia;
In
methanol; dichloromethane; water; dimethyl sulfoxide; acetone;
DOI:10.1021/jo00298a048
