methyl 6-O-acetyl-2-(acetylamino)-2,3,4-trideoxy-4-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)hex-2-enopyranoside

Base Information

• Chemical Name: methyl 6-O-acetyl-2-(acetylamino)-2,3,4-trideoxy-4-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)hex-2-enopyranoside
• CAS No.: 63064-64-2
• Molecular Formula: C18H23N5O7
• Molecular Weight: 421.4045
• Mol file: 63064-64-2.mol

Synonyms:NSC288369

Chemical Property of methyl 6-O-acetyl-2-(acetylamino)-2,3,4-trideoxy-4-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)hex-2-enopyranoside

Chemical Property:

• Refractive Index: 1.645
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.49g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of methyl 6-O-acetyl-2-(acetylamino)-2,3,4-trideoxy-4-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)hex-2-enopyranoside

There total 5 articles about methyl 6-O-acetyl-2-(acetylamino)-2,3,4-trideoxy-4-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)hex-2-enopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

acetic anhydride (108-24-7) + 7-(methyl 2-acetamido-2,3,4-trideoxy-α-D-erythro-hex-2-enopyranosid-4-yl)theophylline monohydrate → 7-(methyl 2-acetamido-6-O-acetyl-2,3,4-trideoxy-α-D-erythro-hex-2-enopyranosid-4-yl)theophylline (63064-64-2)

Guidance literature:

In pyridine; Product distribution; determination of structure;

DOI:10.1016/S0008-6215(00)80523-6

Reference yield: 46.0%

7-(2-acetamido-4,6-di-O-acetyl-2,3-dideoxy-β-D-erythro-hex-2-enopyranosyl)theophylline (80035-38-7) → 7-(methyl 2-acetamido-6-O-acetyl-2,3,4-trideoxy-α-D-erythro-hex-2-enopyranosid-4-yl)theophylline (63064-64-2) + 7-(methyl 2-acetamido-6-O-acetyl-2,3,4-trideoxy-β-D-erythro-hex-2-enopyranosid-4-yl)theophylline (70675-25-1)

Guidance literature:

With boron trifluoride diethyl etherate; In methanol; for 1.5h; Heating;

DOI:10.1016/S0008-6215(00)80524-8

Reference yield: 2.0%

methanol (67-56-1) + theophylline (58-55-9,75448-53-2) + 2-acetamido-3,4,6-tri-O-acetyl-1,5-anhydro-2-deoxy-D-arabino-hex-1-enitol (10293-60-4) → 7-(methyl 2-acetamido-6-O-acetyl-2,3,4-trideoxy-α-D-erythro-hex-2-enopyranosid-4-yl)theophylline (63064-64-2) + 7-(methyl 2-acetamido-6-O-acetyl-2,3,4-trideoxy-α-D-threo-hex-2-enopyranosid-4-yl)theophylline (70800-68-9) + 7-(methyl 2-acetamido-6-O-acetyl-2,3,4-trideoxy-β-D-erythro-hex-2-enopyranosid-4-yl)theophylline (70675-25-1) + 7-(2-acetamido-4,6-di-O-acetyl-2,3-dideoxy-β-D-erythro-hex-2-enopyranosyl)theophylline (80035-38-7)

Guidance literature:

boron trifluoride diethyl etherate; at 85 - 95 ℃; for 2h; Further byproducts given. Yields of byproduct given;

DOI:10.1016/S0008-6215(00)80523-6

upstream raw materials:

methanol

theophylline

2-acetamido-3,4,6-tri-O-acetyl-1,5-anhydro-2-deoxy-D-arabino-hex-1-enitol

acetic anhydride