Hexanoic acid, 6-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester

Base Information

Chemical Name:Hexanoic acid, 6-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester
CAS No.:128372-97-4
Molecular Formula:C12H23NO4
Molecular Weight:245.319
Hs Code.:
Mol file:128372-97-4.mol

Synonyms:

Suppliers and Price of Hexanoic acid, 6-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 3 raw suppliers

Chemical Property of Hexanoic acid, 6-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Hexanoic acid, 6-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester

There total 1 articles about Hexanoic acid, 6-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 6404-29-1
6-(tert-butoxycarbonylamino)hexanoic acid

: 74-88-4
methyl iodide

: 128372-97-4
N-tert-butoxycarbonyl-6-aminohexanoic acid methyl ester

Guidance literature:: With sodium hydrogencarbonate; In N,N-dimethyl-formamide; for 120h; Ambient temperature;

Reference yield:

: 21272-85-5
phenylsulfonylnitromethane

: 128372-97-4
N-tert-butoxycarbonyl-6-aminohexanoic acid methyl ester

: (7-benzenesulfonyl-7-nitrohept-5-enyl)carbamic acid tert-butyl ester

Guidance literature:: N-tert-butoxycarbonyl-6-aminohexanoic acid methyl ester; With diisobutylaluminium hydride; In dichloromethane; at -78 ℃; for 0.5h; Inert atmosphere;

phenylsulfonylnitromethane; With ester of 3,5-di-tert-butyl-4-hydroxyphenylpropionic acid and pentaerythritol; L-proline; In dimethyl sulfoxide; at 20 ℃; for 48h;
DOI:10.1016/j.tet.2019.130883

Reference yield:

: 128372-97-4
N-tert-butoxycarbonyl-6-aminohexanoic acid methyl ester

: 1027081-19-1
6-(3,3,3-triphenyl-propionylamino)-hexanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 10percent aq. HCl / methanol

2: WSC; HOBt; NEt₃ / CHCl₃ / 20 °C

3: 4N aq. NaOH / methanol; CHCl₃ / 20 °C

With sodium hydroxide; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triethylamine; In methanol; chloroform;
DOI:10.1021/jm010480k