5-(2-Hydroxyphenyl)-3-(((3-nitrophenyl)amino)methyl)-1,3,4-oxadiazole-2(3H)-thione

Base Information

Chemical Name:5-(2-Hydroxyphenyl)-3-(((3-nitrophenyl)amino)methyl)-1,3,4-oxadiazole-2(3H)-thione
CAS No.:54543-83-8
Molecular Formula:C₁₅H₁₂N₄O₄S
Molecular Weight:344.351
Hs Code.:
Nikkaji Number:J480.167I

Synonyms:BRN 0581325;1,3,4-Oxadiazole-2(3H)-thione, 5-(2-hydroxyphenyl)-3-(((3-nitrophenyl)amino)methyl)-;5-(2-Hydroxyphenyl)-3-(((3-nitrophenyl)amino)methyl)-1,3,4-oxadiazole-2(3H)-thione;54543-83-8;C15H12N4O4S;C15-H12-N4-O4-S;LS-99221;5-(2-Hydroxyphenyl)-3-[(3-nitrophenyl)aminomethyl]-1,3,4-oxadiazole-2(3H)-thione

Suppliers and Price of 5-(2-Hydroxyphenyl)-3-(((3-nitrophenyl)amino)methyl)-1,3,4-oxadiazole-2(3H)-thione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-(2-Hydroxyphenyl)-3-(((3-nitrophenyl)amino)methyl)-1,3,4-oxadiazole-2(3H)-thione

Chemical Property:

Vapor Pressure:1.75E-11mmHg at 25°C
Boiling Point:534.1°Cat760mmHg
Flash Point:276.8°C
Density:1.55g/cm³
XLogP3:3.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:4
Exact Mass:344.05792605
Heavy Atom Count:24
Complexity:524

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C2=NN(C(=S)O2)CNC3=CC(=CC=C3)[N+](=O)[O-])O

Technology Process of 5-(2-Hydroxyphenyl)-3-(((3-nitrophenyl)amino)methyl)-1,3,4-oxadiazole-2(3H)-thione

There total 2 articles about 5-(2-Hydroxyphenyl)-3-(((3-nitrophenyl)amino)methyl)-1,3,4-oxadiazole-2(3H)-thione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 29638-33-3
5‐(2‐hydroxyphenyl)‐1,3,4‐oxadiazole‐2(3H)‐thione

: 99-09-2
3-nitro-aniline

: 54543-83-8
5-(2-hydroxyphenyl)-3-[(3-nitroanilino)methyl]-2,3-dihydro-1,3,4-oxadiazole-2-thione

Guidance literature:: In ethanol; for 3h;
DOI:10.1016/j.bmc.2005.09.053

Reference yield:

: 936-02-7
2-Hydroxybenzoylhydrazine

: 54543-83-8
5-(2-hydroxyphenyl)-3-[(3-nitroanilino)methyl]-2,3-dihydro-1,3,4-oxadiazole-2-thione

Guidance literature:: Multi-step reaction with 2 steps

1: 84.5 percent / potassium hydroxide / ethanol / 12 h / Heating

2: 80 percent / ethanol / 3 h

With potassium hydroxide; In ethanol;
DOI:10.1016/j.bmc.2005.09.053