Technology Process of 2H-Pyran-2-one, tetrahydro-6-(4-methoxyphenyl)-, (S)-
There total 7 articles about 2H-Pyran-2-one, tetrahydro-6-(4-methoxyphenyl)-, (S)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
methyl 5-(4-methoxyphenyl)pentanoate;
With
ketoreductase-P2-C02; oxygen; NADPH; 9-(2-mesityl)-10-methylacridinium perchlorate;
In
water; acetonitrile;
at 23 ℃;
for 24h;
Irradiation;
Enzymatic reaction;
With
isopropyl alcohol;
In
water; acetonitrile;
enantioselective reaction;
Enzymatic reaction;
DOI:10.1002/anie.201909426
- Guidance literature:
-
With
C35H52N4O4; aluminum ethoxide; 3-chloro-benzenecarboperoxoic acid; scandium tris(trifluoromethanesulfonate);
In
ethyl acetate;
at -20 ℃;
for 18h;
regioselective reaction;
Molecular sieve;
Resolution of racemate;
DOI:10.1021/ol501737a
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: zinc; mercury dichloride; hydrogenchloride / toluene / 4 h / 100 °C / Inert atmosphere; Sealed tube
2.1: sulfuric acid / toluene / 2 h / 80 °C / Inert atmosphere; Sealed tube
3.1: NADPH; 9-(2-mesityl)-10-methylacridinium perchlorate; oxygen; ketoreductase-P2-C02 / acetonitrile; water / 24 h / 23 °C / Irradiation; Enzymatic reaction
3.2: Enzymatic reaction
With
hydrogenchloride; sulfuric acid; ketoreductase-P2-C02; oxygen; NADPH; mercury dichloride; zinc; 9-(2-mesityl)-10-methylacridinium perchlorate;
In
water; toluene; acetonitrile;
DOI:10.1002/anie.201909426
