61349-69-7

Usage

Uses

Used in Pharmaceutical Industry:
Cyclopentanone, 2-(4-methoxyphenyl)is used as a building block for the synthesis of various pharmaceuticals. Its unique chemical structure allows it to be a versatile component in the development of new drugs and medications.
Used in Agrochemical Industry:
Cyclopentanone, 2-(4-methoxyphenyl)is also used as a building block in the synthesis of agrochemicals, contributing to the development of new pesticides, herbicides, and other agricultural products.
Used in Organic Compounds Synthesis:
Cyclopentanone, 2-(4-methoxyphenyl)is utilized as a building block in the synthesis of various organic compounds, expanding its applications in different fields of chemistry.
Used in Fragrance Industry:
It is primarily used as a fragrance ingredient in cosmetic and personal care products, as well as in flavorings and fragrances, due to its sweet, floral, and fruity odor.
Used as a Solvent:
Cyclopentanone, 2-(4-methoxyphenyl)is also used as a solvent and intermediate in the production of other chemicals, further broadening its applications across various industries.
It is important to handle Cyclopentanone, 2-(4-methoxyphenyl)- with care, as it may pose health hazards, and should be used in accordance with proper safety guidelines and regulations.

Upstream product

• 57769-42-3 4-(2,3-epoxy-cyclopentyl)-anisole 
• 5435-44-9 (E)-3-Ureido-but-2-enoic acid ethyl ester 
• 936-52-7 1-(N-morpholino)cyclopent-1-ene 
• 18649-43-9 4-methoxyphenyllead(IV) triacetate 
• 75-77-4 chloro-trimethyl-silane 
• 1847-68-3 5-(4-methoxy-phenyl)-5-oxo-pentanoic acid methyl ester 
• 19980-43-9 1-(trimethylsilyloxy)cyclopentene 
• 694-28-0 2-chlorocyclopentanone 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 1191-95-3 cyclobutanone 
• 23304-25-8 p-methoxyphenyldiazomethane 
• 933674-44-3 2-(4-methoxyphenyl)cyclopentanol 
• 70106-27-3 2-(4-methoxyphenyl)cyclobutan-1-one 
• 18107-18-1 diazomethyl-trimethyl-silane 

Downstream Products

• 61321-34-4 2-(4-methoxyphenyl)-2-<2-(dimethylamino)ethyl>cyclopentanone hydrobromide 
• 381226-47-7 C₁₆H₂₀O₃ 
• 1253111-91-9 (2S,3S)-2-(4-methoxyphenyl)-2-(2-nitro-1-phenylethyl)cyclopentanone 
• 129098-68-6 (-)-6-(4-methoxyphenyl)tetrahydro-2H-pyran-2-one 
• 34665-81-1 5-hydroxy-5-(4-methoxyphenyl)valeric acid δ lactone 

Relevant academic research and scientific papers

Enantioselective Radical Ring-Opening Cyanation of Oxime Esters by Dual Photoredox and Copper Catalysis

Catalytic enantioselective chemical reactions involving highly reactive radical species remain largely unexplored. We report herein for the first time a novel enantioselective radical ring-opening cyanation of redox-active oxime esters by dual photoreodox

Catalytic asymmetric synthesis of sterically hindered tertiary α-aryl ketones

The catalytic asymmetric synthesis of a series of tertiary α-aryl cyclopentanones and cyclohexanones has been accomplished via a Pd-catalyzed decarboxylative protonation of the corresponding α-aryl-β-keto allyl esters. Enantioselectivities of up to 92% ee and 74% ee were achieved for cyclopentanone and cyclohexanone substrates, respectively. The route described gives access to these important structural motifs in moderate to high levels of enantioselectivity. In particular, this is only the second direct approach for the preparation of tertiary α-aryl cyclopentanones. The synthetic approach allows for simple modification of the aryl group. Significantly, substrates containing sterically hindered aryl groups gave the highest levels of enantioselectivity, and these aryl groups were readily installed by a Pb-mediated arylation of a β-keto allyl ester.

Regio- and enantioselective Baeyer-Villiger oxidation: Kinetic resolution of racemic 2-substituted cyclopentanones

A kinetic resolution of racemic 2-substituted cyclopentanones via highly regio- and enantioselective Baeyer-Villiger oxidation has been successfully developed. The reaction could afford the normal 6-substituted δ-lactones in up to 98% ee and >19/1 regioselectivity. Meanwhile, the unreacted ketones were recovered in excellent ee values (up to 98%). It represents the best results of the kinetic resolution of racemic 2-substituted cyclopentanones via nonenzymic asymmetric BV oxidation.

Catalytic and regioselective ring expansion of arylcyclobutanones with trimethylsilyldiazomethane. Ligand-dependent entry to β-ketosilane or enolsilane adducts

Divergent reactivity is uncovered in the homologation of arylcyclobutanones with trimethylsilyldiazomethane. With Sc(OTf)3 as catalyst, enolsilanes are obtained with a high preference for methylene migration. By contrast, Sc(hfac)3 g

The 2-(2-Azidoethyl)cycloalkanone strategy for bridged amides and medium-sized cyclic amine derivatives in the Aubé-Schmidt reaction

2-(2-Azidoethyl)cycloalkanones afford bridged lactams in the Aubé-Schmidt reaction, sometimes in excellent yield, and solvolysis yields derivatives of medium-ring amines. Attempts to divert the Schmidt reaction with an arene-mediated fragmentation of the normal Schmidt intermediate have led to an initial example. Georg Thieme Verlag Stuttgart.

Cycloalkyl alkanoic acids as integrin receptor antagonists derivatives

The present invention relates to a class of compounds represented by the Formula I or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula I, and methods of selectively inhibiting or antagonizing the αvβ3 and/or αvβ5 integrin.

Electroreductive intramolecular coupling of aromatic δ- and ε-keto esters

Electroreduction of aromatic δ- and ε-keto esters in the presence of chlorotrimethylsilane and triethylamine gave five- and six-membered cyclized products. The products were transformed to the corresponding α-hydroxy ketones.

THE SYNTHESIS VIA ORGANOIRON COMPLEXES OF PEDICELLANIN METHYL ETHER AND CUPARENE

A synthetic route to Pedicellanin methyl ether as well as to Cuparene via iron tricarbonyl-cyclohexadienyl cations is reported.The unusual aromatization reaction of the iron tricarbonyl- cyclohexadienyl mojety by iron trichloride is evidencied.

The Chemistry of Aryllead(IV) Tricarboxylates. Reaction with Enamines

The treatment of 1-morhpholinocyclopentene (1a) with p-methoxyphenyllead triacetate (2a) in chloroform provides a simple high-yielding route to 2-(4-methoxyphenyl)cyclopentanone (3a).This arylation reaction of enamines has been investigated with a variety of substrates and a number of aryllead triacetates.The reaction has been found to be very sensitive to steric effects and is thus a useful synthetic method in a relatively small number of cases.Acetoxylation is a major competing reaction with those enamines of cyclic ketones which give a low to moderate yield of arylated product.