Amino-PEG10-alcohol

Base Information

• Chemical Name: Amino-PEG10-alcohol
• CAS No.: 129449-09-8
• Molecular Formula: C20H43NO10
• Molecular Weight: 457.55600
• Hs Code.: 2918999090
• Mol file: 129449-09-8.mol

Synonyms:2-{2-[2-(2-{2-[2-(2-{2-[2-(2-Amino-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethanol;29-amino-3,6,9,12,15,18,21,24,27-nonaoxanonacosanol;

Chemical Property of Amino-PEG10-alcohol

Chemical Property:

• Boiling Point: 533.3±45.0 °C(Predicted)
• PKA: 14.36±0.10(Predicted)
• PSA: 129.32000
• Density: 1.096±0.06 g/cm3(Predicted)
• LogP: -0.21290

Purity/Quality:

99.3% ^*data from raw suppliers

Amino-PEG10-alcohol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Description: Amino-PEG10-alcohol is a highly water soluble PEG reagent. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

Technology Process of Amino-PEG10-alcohol

There total 13 articles about Amino-PEG10-alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-azido-29-hydroxy-3,6,9,12,15,18,21,24,27-nonaoxanonacosane (877239-09-3) → 29-amino-3,6,9,12,15,18,21,24,27-nonaoxanonacosan-1-ol (129449-09-8)

Guidance literature:

1-azido-29-hydroxy-3,6,9,12,15,18,21,24,27-nonaoxanonacosane; With triphenylphosphine; In tetrahydrofuran; at 20 - 50 ℃; for 25h;

With water; In tetrahydrofuran; Further stages.;

DOI:10.1021/jo0012290

Reference yield: 67.0%

→ 29-amino-3,6,9,12,15,18,21,24,27-nonaoxanonacosan-1-ol (129449-09-8)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol;

Reference yield:

1-azide-31,31,31-triphenyl-3,6,9,12,15,18,21,24,27,30-decaoxahentriacontanol (877239-08-2) → 29-amino-3,6,9,12,15,18,21,24,27-nonaoxanonacosan-1-ol (129449-09-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 0.22 g / p-TsOH / methanol / 2 h / 20 °C

2.1: Ph₃P / tetrahydrofuran / 25 h / 20 - 50 °C

2.2: 100 percent / H₂O / tetrahydrofuran

With toluene-4-sulfonic acid; triphenylphosphine; In tetrahydrofuran; methanol; 2.1: Staudinger reduction reaction;

DOI:10.1021/jo0012290

upstream raw materials:

1-azido-29-hydroxy-3,6,9,12,15,18,21,24,27-nonaoxanonacosane

Tetraethylene glycol

pentaethylene glycol

17-azido-3,6,9,12,15-pentaoxaheptadecan-1-ol

Downstream raw materials:

2-((4S)-6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepin-4-yl)-N-(29-hydroxy-3,6,9,12,15,18,21,24,27-nonaoxanonacosyl)acetamide

N-(29-(((4S)-6-(4-chlorophenyl)-4-(2-(ethylamino)-2-oxoethyl)-1-methyl-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepin-8-yl)oxy)-3,6,9,12,15,18,21,24,27-nonaoxanonacosyl)-2-((4S)-6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepin-4-yl)acetamide

1-((4S)-6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepin-4-yl)-2-oxo-6,9,12,15,18,21,24,27,30-nonaoxa-3-azadotriacontan-32-yl methanesulfonate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 129449-09-8 Amino-PEG10-alcohol

Send

Send

Metric Ton KG G Pound L ML

Send

Send