1-Methoxy-2-(3,3,3-trifluoroprop-1-yn-1-yl)benzene

Base Information

Chemical Name:1-Methoxy-2-(3,3,3-trifluoroprop-1-yn-1-yl)benzene
CAS No.:130654-80-7
Molecular Formula:C10H7F3O
Molecular Weight:200.16
Hs Code.:
DSSTox Substance ID:DTXSID30563032
Nikkaji Number:J331.217H
Wikidata:Q82447374

Synonyms:130654-80-7;1-Methoxy-2-(3,3,3-trifluoroprop-1-yn-1-yl)benzene;DTXSID30563032

Suppliers and Price of 1-Methoxy-2-(3,3,3-trifluoroprop-1-yn-1-yl)benzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 1-Methoxy-2-(3,3,3-trifluoroprop-1-yn-1-yl)benzene

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:200.04489933
Heavy Atom Count:14
Complexity:245

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC=C1C#CC(F)(F)F

Technology Process of 1-Methoxy-2-(3,3,3-trifluoroprop-1-yn-1-yl)benzene

There total 11 articles about 1-Methoxy-2-(3,3,3-trifluoroprop-1-yn-1-yl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 1514-82-5
2-bromo-3,3,3-trifluoropropene

: 529-28-2
4-iodoanisol

: 130654-80-7
1-methoxy-2-(3,3,3-trifluoroprop-1-yn-1-yl)benzene

Guidance literature:: 2-bromo-3,3,3-trifluoropropene; With dichloro(N,N,N’,N‘-tetramethylethylenediamine)zinc; lithium diisopropyl amide; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 1h;

4-iodoanisol; With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; hexane; for 12h; Heating;
DOI:10.1016/S0040-4020(03)01199-2

Reference yield: 78.0%

: 529-28-2
4-iodoanisol

: 672339-38-7
(Z)-2,3,3,3-tetrafluoro-1-iodoprop-1-ene

: 130654-80-7
1-methoxy-2-(3,3,3-trifluoroprop-1-yn-1-yl)benzene

Guidance literature:: (Z)-2,3,3,3-tetrafluoro-1-iodoprop-1-ene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃;

With dichloro(N,N,N’,N‘-tetramethylethylenediamine)zinc; In tetrahydrofuran; hexane; at -78 - 20 ℃;

4-iodoanisol; With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; hexane; at 60 ℃; for 12h;
DOI:10.1016/S0040-4020(03)01199-2

Reference yield: 74.0%

: [(2-methoxyphenyl)ethynyl]copper

: 81290-20-2
(trifluoromethyl)trimethylsilane

: 130654-80-7
1-methoxy-2-(3,3,3-trifluoroprop-1-yn-1-yl)benzene

Guidance literature:: With N,N,N,N,-tetramethylethylenediamine; In N,N-dimethyl-formamide; Petroleum ether; at 20 ℃; for 24h; Inert atmosphere;
DOI:10.1002/adsc.201400057