1,2-phenylenebis(ethane-2,1-diyl) diMethanesulfonate

Base Information

• Chemical Name: 1,2-phenylenebis(ethane-2,1-diyl) diMethanesulfonate
• CAS No.: 130800-04-3
• Molecular Formula: C12H18O6S2
• Molecular Weight: 322.403
• Mol file: 130800-04-3.mol

Synonyms:1,2-Benzenediethanol, dimethanesulfonate

Chemical Property of 1,2-phenylenebis(ethane-2,1-diyl) diMethanesulfonate

Chemical Property:

• PSA: 165.96000
• LogP: 1.92580

Purity/Quality:

99.3% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,2-phenylenebis(ethane-2,1-diyl) diMethanesulfonate

There total 2 articles about 1,2-phenylenebis(ethane-2,1-diyl) diMethanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2,2’-(1,2-phenylene)diethanol (17378-99-3) + methanesulfonyl chloride (124-63-0) → 1,2-phenylenebis(ethane-2,1-diyl) dimethanesulfonate (130800-04-3)

Guidance literature:

With triethylamine; In dichloromethane; at 0 ℃; for 0.5h;

Reference yield:

1,2-Phenylenediacetic acid (7500-53-0) → 1,2-phenylenebis(ethane-2,1-diyl) dimethanesulfonate (130800-04-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 96 percent / LiAlH₄ / tetrahydrofuran / Ambient temperature

2: 97 percent / triethylamine

With lithium aluminium tetrahydride; triethylamine; In tetrahydrofuran;

DOI:10.1021/jo00003a050

Reference yield: 100.0%

1,2-phenylenebis(ethane-2,1-diyl) dimethanesulfonate (130800-04-3) → 2,3,4,5-tetrahydro-1H-3-benzazepine (4424-20-8)

Guidance literature:

With ammonia; at 90 ℃; for 3h; Sealed tube;

upstream raw materials:

2,2’-(1,2-phenylene)diethanol

methanesulfonyl chloride

1,2-Phenylenediacetic acid

Downstream raw materials:

1,2-Bis(2'-iodoethyl)benzene

2,3,4,5-tetrahydro-1H-3-benzazepine

7-nitro-2,3,4,5-tetrahydro-1H-benzo[d]azepiney