thiaminocycline

Base Information

Chemical Name:thiaminocycline
CAS No.:82925-85-7
Molecular Formula:C₂₂H₂₅N₃O₇S
Molecular Weight:475.522
Hs Code.:
Mol file:82925-85-7.mol

Synonyms:10H-Benzo[b]thioxanthene-9-carboxamide,4,7-bis(dimethylamino)-5a,6,6a,7,10a,12-hexahydro-1,8,10a,11-tetrahydroxy-10,12-dioxo-,(5aa,6aa,7a,10aa)-(?à)-

Suppliers and Price of thiaminocycline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of thiaminocycline

Chemical Property:

Vapor Pressure:5.72E-21mmHg at 25°C
Boiling Point:706.8°C at 760 mmHg
Flash Point:381.3°C
PSA：190.92000
Density:1.62g/cm³
LogP:1.48170

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of thiaminocycline

There total 4 articles about thiaminocycline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 82925-84-6
4-Amino-7-dimethylamino-3,10,12,12aα-tetrahydroxy-1,4β,4aα,5,5aα,6,11,12a-oktahydro-1,11-dioxo-6-thianaphthacen-2-carboxamid-dihydrochlorid

: 82925-85-7
6-Thia-minocyclin

Guidance literature:: With sodium cyanoborohydride; triethylamine; In tetrahydrofuran; for 0.25h;
DOI:10.1002/ardp.19823150608

Reference yield:

: 82925-83-5
(+/-)-7-Dimethylamino-3,10,12,12aα-tetrahydroxy-4-thiabenzamido-1,4β,4aα,5,5aα,6,11,12a-oktahydro-1,11-dioxo-6-thianaphthacen-2-carboxamid

: 82925-85-7
6-Thia-minocyclin

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) Et₃OBF₄, 2.) 10percent aq. HCl / 1.) CH₂Cl₂, 15 min, 2.) THF, 2 h

2: 36 percent / Et₃N, NaBH₃CN / tetrahydrofuran / 0.25 h

With hydrogenchloride; triethyloxonium fluoroborate; sodium cyanoborohydride; triethylamine; In tetrahydrofuran;
DOI:10.1002/ardp.19823150608

Reference yield:

: 70098-67-8,70116-55-1,82950-78-5
7-Dimethylamino-4-thiobenzamido-3,10,12-trihydroxy-1,4,4a,5,5a,6,11,12a-oktahydro-1,11-dioxo-6-thianaphthacen-2-carboxamid

: 82925-85-7
6-Thia-minocyclin

Guidance literature:: Multi-step reaction with 4 steps

1: piperidine / 3 h / 50 °C

2: 42 percent / 1.) (EtO)3PO, CH₃ONa, 2.) tert-BuOK, O₂ / dimethylformamide / 1.) -14 deg C, 1 h, 2.) -2 deg C, 5 min

3: 1.) Et₃OBF₄, 2.) 10percent aq. HCl / 1.) CH₂Cl₂, 15 min, 2.) THF, 2 h

4: 36 percent / Et₃N, NaBH₃CN / tetrahydrofuran / 0.25 h

With piperidine; hydrogenchloride; triethyl phosphate; potassium tert-butylate; oxygen; sodium methylate; triethyloxonium fluoroborate; sodium cyanoborohydride; triethylamine; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1002/ardp.19823150608