2-Hydroxy-3-methylbut-3-enenitrile

Base Information

Chemical Name:2-Hydroxy-3-methylbut-3-enenitrile
CAS No.:22410-56-6
Molecular Formula:C₅H₇NO
Molecular Weight:97.1167
Hs Code.:
NSC Number:32612
DSSTox Substance ID:DTXSID40283633
Mol file:22410-56-6.mol

Synonyms:2-hydroxy-3-methylbut-3-enenitrile;22410-56-6;3-Butenenitrile,2-hydroxy-3-methyl-;NSC32612;DTXSID40283633;NSC-32612;AKOS026726371;EN300-157371

Suppliers and Price of 2-Hydroxy-3-methylbut-3-enenitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 2-Hydroxy-3-methylbut-3-enenitrile

Chemical Property:

Vapor Pressure:0.0543mmHg at 25°C
Boiling Point:206.9°Cat760mmHg
Flash Point:78.9°C
Density:0.998g/cm³
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:97.052763847
Heavy Atom Count:7
Complexity:119

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=C)C(C#N)O

Technology Process of 2-Hydroxy-3-methylbut-3-enenitrile

There total 3 articles about 2-Hydroxy-3-methylbut-3-enenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 78-85-3,25120-30-3
2-methylpropenal

: 74-90-8
hydrogen cyanide

: 22410-56-6,147600-17-7
2-hydroxy-3-methylbut-3-enenitrile

Guidance literature:: With triethylamine; In dichloromethane; 1.) 1h 0 deg C; 2.) 30 min r.t.;
DOI:10.1021/jo01291a005

Reference yield: 75.0%

: 78-85-3,25120-30-3
2-methylpropenal

: 7677-24-9
trimethylsilyl cyanide

: 22410-56-6,147600-17-7
2-hydroxy-3-methylbut-3-enenitrile

Guidance literature:: With titanium complex of binaphthyl Schiff base; In dichloromethane; at -78 ℃; for 120h;
DOI:10.1039/a904330f

Reference yield:

: 78-85-3,25120-30-3
2-methylpropenal

: 143-33-9,25596-52-5
sodium cyanide

: 22410-56-6,147600-17-7
2-hydroxy-3-methylbut-3-enenitrile

Guidance literature:: sodium cyanide; With acetic acid; In diethyl ether; at 0 ℃; for 0.5h; Inert atmosphere;

2-methylpropenal; In diethyl ether; at 0 - 20 ℃;
DOI:10.1021/ol8018852