6H-Benzofuro[3,2-c][1]benzopyran-3,6a,9(11aH)-triol, 9CI

Base Information

Chemical Name:6H-Benzofuro[3,2-c][1]benzopyran-3,6a,9(11aH)-triol, 9CI
CAS No.:69393-95-9
Molecular Formula:C15H12 O5
Molecular Weight:272.257
Hs Code.:
Wikidata:Q105224237
Mol file:69393-95-9.mol

Synonyms:6AS11AS-36A9-TRIHYDROXYPTEROCARPAN;6H-Benzofuro[3,2-c][1]benzopyran-3,6a,9(11aH)-triol, 9CI

Suppliers and Price of 6H-Benzofuro[3,2-c][1]benzopyran-3,6a,9(11aH)-triol, 9CI

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Arctom
Glycinol ≥98%
5mg
$ 398.00

Total 3 raw suppliers

Chemical Property of 6H-Benzofuro[3,2-c][1]benzopyran-3,6a,9(11aH)-triol, 9CI

Chemical Property:

Vapor Pressure:6.21E-12mmHg at 25°C
Boiling Point:527°C at 760 mmHg
Flash Point:272.5°C
PSA：79.15000
Density:1.592g/cm³
LogP:1.81150
XLogP3:1.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:0
Exact Mass:272.06847348
Heavy Atom Count:20
Complexity:389

Purity/Quality:

99% ^*data from raw suppliers

Glycinol ≥98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C2(C(C3=C(O1)C=C(C=C3)O)OC4=C2C=CC(=C4)O)O

Technology Process of 6H-Benzofuro[3,2-c][1]benzopyran-3,6a,9(11aH)-triol, 9CI

There total 2 articles about 6H-Benzofuro[3,2-c][1]benzopyran-3,6a,9(11aH)-triol, 9CI which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: glycinol-3-O-β-D-glucopyranoside

: 69393-95-9
6a,11a-dihydro-6H-benzofuro[3,2-c]chromen-3,6a,9-triol

: 2280-44-6
D-Glucose

Guidance literature:: With hydrogenchloride; water; In 1,4-dioxane; at 80 ℃; for 3h;
DOI:10.1016/j.bmcl.2014.05.077

Reference yield:

: 22532-60-1
2-bromo-4-hydroxybenzaldehyde

: 69393-95-9
6a,11a-dihydro-6H-benzofuro[3,2-c]chromen-3,6a,9-triol

Guidance literature:: Multi-step reaction with 11 steps

1.1: potassium carbonate / N,N-dimethyl-formamide / 6 h / 70 °C

2.1: tetrahydrofuran; ethanol / 6 h / 0 °C / Reflux

3.1: magnesium bromide / diethyl ether / 2 h / 20 °C

4.1: 6-chloro-5-phenylpyrimidine-4-(9-O-quinidine) ether; tetra-(n-butyl)ammonium iodide; N,N,N',N'-tetramethyl-1,8-diaminonaphthalene / tetrahydrofuran / 0.5 h / -78 °C

5.1: potassium tert-butylate / tetrahydrofuran / 2 h / 0 °C

6.1: triethylamine / dichloromethane / 3 h / 20 °C

7.1: lithium borohydride / tetrahydrofuran / 0 - 20 °C

8.1: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; monophosphine 1,2,3,4,5-pentaphenyl-1'-(di-tert-butylphosphino)ferrocene; caesium carbonate / toluene / 7 h / 90 °C / Inert atmosphere

9.1: lithium borohydride; nickel dichloride / tetrahydrofuran / 7 h / Reflux

10.1: pyridine; Dess-Martin periodane / dichloromethane / 1 h / Reflux

10.2: 0.67 h / Reflux

11.1: palladium on carbon; cyclohexa-1,4-diene / ethanol / 24 h / 20 °C

With pyridine; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; lithium borohydride; monophosphine 1,2,3,4,5-pentaphenyl-1'-(di-tert-butylphosphino)ferrocene; cyclohexa-1,4-diene; palladium on carbon; 6-chloro-5-phenylpyrimidine-4-(9-O-quinidine) ether; potassium tert-butylate; tetra-(n-butyl)ammonium iodide; N,N,N',N'-tetramethyl-1,8-diaminonaphthalene; potassium carbonate; caesium carbonate; Dess-Martin periodane; triethylamine; magnesium bromide; nickel dichloride; In tetrahydrofuran; diethyl ether; ethanol; dichloromethane; N,N-dimethyl-formamide; toluene; 2.1: Darzens condensation / 4.1: Feist-Benary interrupted synthesis;
DOI:10.1021/ol201332u