Glycine, N-[(1,1-dimethylethoxy)carbonyl]glycyl-N-methyl-

Base Information

Chemical Name:Glycine, N-[(1,1-dimethylethoxy)carbonyl]glycyl-N-methyl-
CAS No.:133498-97-2
Molecular Formula:C10H18N2O5
Molecular Weight:246.263
Hs Code.:
DSSTox Substance ID:DTXSID00450546

Synonyms:133498-97-2;Glycine, N-[(1,1-dimethylethoxy)carbonyl]glycyl-N-methyl-;2-(2-((tert-Butoxycarbonyl)amino)-N-methylacetamido)acetic acid;Boc-Gly-Sar-OH;2-[methyl-[2-[(2-methylpropan-2-yl)oxycarbonylamino]acetyl]amino]acetic Acid;2-(2-{[(tert-butoxy)carbonyl]amino}-N-methylacetamido)acetic acid;[N-(tert-butoxycarbonyl)-glycyl]-sarcosine;SCHEMBL1456111;DTXSID00450546;VNYXZTSJRJLBSO-UHFFFAOYSA-N;MFCD24465606;BS-15066;CS-0161672;D83876

Suppliers and Price of Glycine, N-[(1,1-dimethylethoxy)carbonyl]glycyl-N-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Glycine, N-[(1,1-dimethylethoxy)carbonyl]glycyl-N-methyl-

Chemical Property:

XLogP3:0.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:246.12157168
Heavy Atom Count:17
Complexity:308

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NCC(=O)N(C)CC(=O)O

Technology Process of Glycine, N-[(1,1-dimethylethoxy)carbonyl]glycyl-N-methyl-

There total 5 articles about Glycine, N-[(1,1-dimethylethoxy)carbonyl]glycyl-N-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 174311-10-5
methyl N'-(tert-butoxycarbonyl)glycylsarcosinate

: 133498-97-2
t-BuOCO-Gly-Sar-OH

Guidance literature:: With lithium hydroxide;
DOI:10.1021/ja00077a082

Reference yield: 99.0%

: 73243-15-9
t-BuOCO-Gly-Sar-OCH₂Ph₂

: 133498-97-2
t-BuOCO-Gly-Sar-OH

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; for 18h; Ambient temperature;
DOI:10.1002/hlca.19910740121

Reference yield:

: 4530-20-5
BOC-glycine

: 133498-97-2
t-BuOCO-Gly-Sar-OH

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / Et₃N, DCC, DMAP / CH₂Cl₂ / 20 h / 25 °C

2: 100 percent / LiOH*H₂O / tetrahydrofuran; methanol; H₂O / 3 h / 25 °C

With dmap; lithium hydroxide; triethylamine; dicyclohexyl-carbodiimide; In tetrahydrofuran; methanol; dichloromethane; water;
DOI:10.1021/ja952799y