2H-Pyran, tetrahydro-2-[4-(trifluoromethyl)phenoxy]-

Base Information

Chemical Name:2H-Pyran, tetrahydro-2-[4-(trifluoromethyl)phenoxy]-
CAS No.:134142-88-4
Molecular Formula:C12H13F3O2
Molecular Weight:246.229
Hs Code.:
DSSTox Substance ID:DTXSID30463442
Nikkaji Number:J1.665.564C

Synonyms:134142-88-4;2H-Pyran, tetrahydro-2-[4-(trifluoromethyl)phenoxy]-;2-(4-(trifluoromethyl)phenoxy)tetrahydropyran;2-[4-(TRIFLUOROMETHYL)PHENOXY]TETRAHYDRO-2H-PYRAN;SCHEMBL1714946;DTXSID30463442;F94851;4-(trifluoromethyl)phenyl 2-tetrahydropyranyl ether;Tetrahydro-2-[4-(trifluoromethyl)phenoxy]-2H-pyran

Suppliers and Price of 2H-Pyran, tetrahydro-2-[4-(trifluoromethyl)phenoxy]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 2H-Pyran, tetrahydro-2-[4-(trifluoromethyl)phenoxy]-

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:246.08676414
Heavy Atom Count:17
Complexity:234

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCOC(C1)OC2=CC=C(C=C2)C(F)(F)F

Technology Process of 2H-Pyran, tetrahydro-2-[4-(trifluoromethyl)phenoxy]-

There total 2 articles about 2H-Pyran, tetrahydro-2-[4-(trifluoromethyl)phenoxy]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 110-87-2
3,4-dihydro-2H-pyran

: 402-45-9
4-hydroxybenzotrifluoride

: 134142-88-4
2-[(4-trifluoromethyl)phenoxy]tetrahydro-2H-pyrane

Guidance literature:: In diethyl ether; dichloromethane; at 0 - 20 ℃;

Reference yield: 67.0%

: 81290-20-2
(trifluoromethyl)trimethylsilane

: 99522-34-6
4-[(tetrahydro-2H-pyran-2-yl)oxy]iodobenzene

: 134142-88-4
2-[(4-trifluoromethyl)phenoxy]tetrahydro-2H-pyrane

Guidance literature:: With potassium fluoride; copper(l) iodide; 1,10-Phenanthroline; Trimethyl borate; In dimethyl sulfoxide; at 60 ℃; for 24h; Inert atmosphere;
DOI:10.1021/ol501967c

Reference yield: 89.0%

: 134142-88-4
2-[(4-trifluoromethyl)phenoxy]tetrahydro-2H-pyrane

: 400091-57-8
2-[2-chloro-4-(trifluoromethyl)phenoxy]tetrahydro-2H-pyran

Guidance literature:: 3-[4-(trifluoromethyl)phenoyl]tetrahydro-2-H-pyran; With n-butyllithium; In tetrahydrofuran; hexane; at -70 ℃; for 0.5h;

With hexachloroethane; In tetrahydrofuran; hexane; at -70 - 20 ℃;
DOI:10.1055/s-2001-18440