Ethanimidoyl iodide, 2,2,2-trifluoro-N-(4-methoxyphenyl)-

Base Information

• Chemical Name: Ethanimidoyl iodide, 2,2,2-trifluoro-N-(4-methoxyphenyl)-
• CAS No.: 134481-27-9
• Molecular Formula: C9H7F3INO
• Molecular Weight: 329.06
• DSSTox Substance ID: DTXSID20434323
• Nikkaji Number: J519.467I
• Mol file: 134481-27-9.mol

Synonyms:Ethanimidoyl iodide, 2,2,2-trifluoro-N-(4-methoxyphenyl)-;134481-27-9;DTXSID20434323;BSAIUJHXJSDJLI-UHFFFAOYSA-N;1-Iodo-2,2,2-trifluoro-N-(4-methoxyphenyl)ethanimine

Chemical Property of Ethanimidoyl iodide, 2,2,2-trifluoro-N-(4-methoxyphenyl)-

Chemical Property:

• XLogP3: 3.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2
• Exact Mass: 328.95245
• Heavy Atom Count: 15
• Complexity: 234

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)N=C(C(F)(F)F)I

Technology Process of Ethanimidoyl iodide, 2,2,2-trifluoro-N-(4-methoxyphenyl)-

There total 7 articles about Ethanimidoyl iodide, 2,2,2-trifluoro-N-(4-methoxyphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

N-(4-methoxyphenyl)trifluoroacetimidoyl chloride (75999-66-5) → N-(4-methoxyphenyl)-2,2,2-trifluoroacetimidoyl iodide (134481-27-9)

Guidance literature:

With sodium iodide; In acetone;

DOI:10.1016/0040-4039(91)80358-D

Reference yield: 35.0%

iodotrifluoromethane (2314-97-8,263005-66-9) + p-methoxyphenylisonitrile (10349-38-9) → N-(4-methoxyphenyl)-2,2,2-trifluoroacetimidoyl iodide (134481-27-9)

Guidance literature:

With sodium dithionite; sodium carbonate; In water; acetonitrile; at 10 - 15 ℃; for 1h;

DOI:10.1016/0040-4039(96)01808-4

Reference yield:

(Z)-2,2,2-trifluoro-N-(4-methoxyphenyl)acetimidoyl chloride (75999-66-5) → N-(p-Anisyl)-2,2,2-trifluoroacetimidoyl iodide (134481-27-9)

Guidance literature:

With sodium iodide; In acetone; Yield given; Ambient temperature; overnight;

DOI:10.1021/jo00053a011

upstream raw materials:

N-(4-methoxyphenyl)trifluoroacetimidoyl chloride

iodotrifluoromethane

p-methoxyphenylisonitrile

4-methoxy-aniline

Downstream raw materials:

ethyl 3,3,3-trifluoro-2-((4-methoxyphenyl)imino)propanoate

(E)-5,5,5-Trifluoro-4-[(E)-4-methoxy-phenylimino]-pent-2-enoic acid methyl ester

(E)-4,4,4-Trifluoro-3-(4-methoxy-phenylamino)-1-phenyl-but-2-en-1-one

4-methoxy-N-(1,1,1-trifluoro-4-phenylbut-3-yn-2-ylidene)aniline