(4-Methoxy-phenyl)-[1-trifluoromethyl-3-trimethylsilanyl-prop-2-yn-(E)-ylidene]-amine

Base Information

• Chemical Name: (4-Methoxy-phenyl)-[1-trifluoromethyl-3-trimethylsilanyl-prop-2-yn-(E)-ylidene]-amine
• CAS No.: 204130-94-9
• Molecular Formula: C₁₄H₁₆F₃NOSi
• Molecular Weight: 299.368
• Mol file: 204130-94-9.mol

Synonyms:(4-Methoxy-phenyl)-[1-trifluoromethyl-3-trimethylsilanyl-prop-2-yn-(E)-ylidene]-amine

Chemical Property of (4-Methoxy-phenyl)-[1-trifluoromethyl-3-trimethylsilanyl-prop-2-yn-(E)-ylidene]-amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4-Methoxy-phenyl)-[1-trifluoromethyl-3-trimethylsilanyl-prop-2-yn-(E)-ylidene]-amine

There total 1 articles about (4-Methoxy-phenyl)-[1-trifluoromethyl-3-trimethylsilanyl-prop-2-yn-(E)-ylidene]-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

N-(4-methoxyphenyl)-2,2,2-trifluoroacetimidoyl iodide (134481-27-9) + trimethylsilylacetylene (1066-54-2) → (4-Methoxy-phenyl)-[1-trifluoromethyl-3-trimethylsilanyl-prop-2-yn-(E)-ylidene]-amine (204130-94-9)

Guidance literature:

With triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; In acetonitrile; at 25 ℃; for 30h;

DOI:10.1016/S0022-1139(97)00119-X

Reference yield: 89.0%

benzamidine monohydrochloride (1670-14-0) + (4-Methoxy-phenyl)-[1-trifluoromethyl-3-trimethylsilanyl-prop-2-yn-(E)-ylidene]-amine (204130-94-9) → 2-phenyl-4-(trifluoromethyl)pyrimidine

Guidance literature:

With potassium carbonate; In 1,4-dioxane; for 12h; Heating;

DOI:10.1016/S0022-1139(97)00119-X

upstream raw materials:

N-(4-methoxyphenyl)-2,2,2-trifluoroacetimidoyl iodide

trimethylsilylacetylene