2-Hydroxy-1-(4-methoxyphenyl)-2-(methylsulfanyl)ethan-1-one

Base Information

Chemical Name:2-Hydroxy-1-(4-methoxyphenyl)-2-(methylsulfanyl)ethan-1-one
CAS No.:13603-51-5
Molecular Formula:C10H12O3S
Molecular Weight:212.269
Hs Code.:
DSSTox Substance ID:DTXSID80544831
Mol file:13603-51-5.mol

Synonyms:13603-51-5;SCHEMBL10350128;DTXSID80544831;2-Hydroxy-1-(4-methoxyphenyl)-2-(methylsulfanyl)ethan-1-one

Suppliers and Price of 2-Hydroxy-1-(4-methoxyphenyl)-2-(methylsulfanyl)ethan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2-Hydroxy-1-(4-methoxyphenyl)-2-(methylsulfanyl)ethan-1-one

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:212.05071541
Heavy Atom Count:14
Complexity:188

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C(=O)C(O)SC

Technology Process of 2-Hydroxy-1-(4-methoxyphenyl)-2-(methylsulfanyl)ethan-1-one

There total 5 articles about 2-Hydroxy-1-(4-methoxyphenyl)-2-(methylsulfanyl)ethan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 2813-23-2
2-(4-methoxyphenyl)-2-oxoethyl methyl sulfoxide

: 13603-51-5
2-hydroxy-1-(4-methoxyphenyl)-2-(methylsulfanyl)ethan-1-one

Guidance literature:: With hydrogenchloride; In water; dimethyl sulfoxide; at 20 ℃; for 24h; Inert atmosphere;
DOI:10.1055/s-0031-1289613

Reference yield:

: 63523-19-3
1-(4-Methoxy-phenyl)-3-thioxo-butan-1-one

: 13603-51-5
2-hydroxy-1-(4-methoxyphenyl)-2-(methylsulfanyl)ethan-1-one

Guidance literature:: With hydrogenchloride; water; dimethyl sulfoxide; at 23 ℃; for 24h;
DOI:10.1016/j.tetasy.2017.08.010

Reference yield:

: 94-30-4
ethyl 4-methoxybenzoate

: 13603-51-5
2-hydroxy-1-(4-methoxyphenyl)-2-(methylsulfanyl)ethan-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydride / mineral oil / 1 h / 70 °C / Inert atmosphere

2: hydrogenchloride / water; dimethyl sulfoxide / 24 h / 20 °C / Inert atmosphere

With hydrogenchloride; sodium hydride; In water; dimethyl sulfoxide; mineral oil; 2: Pummerer reaction;
DOI:10.1055/s-0031-1289613