SODIUM METHANESULFONATE

Base Information

• Chemical Name: SODIUM METHANESULFONATE
• CAS No.: 2386-57-4
• Molecular Formula: CH4NaO3S
• Molecular Weight: 118.089
• Hs Code.: 29041000
• Mol file: 2386-57-4.mol

Synonyms:Sodium mesylate;Methanesulfonicacid, sodium salt (8CI,9CI);

Chemical Property of SODIUM METHANESULFONATE

Chemical Property:

• Vapor Pressure: 27.1hPa at 20℃
• Melting Point: 17-19C
• Refractive Index: 1,429-1,431
• Boiling Point: 167C
• PSA: 65.58000
• Density: 1,481g/cm
• LogP: 0.24220
• Storage Temp.: Inert atmosphere,Room Temperature
• Sensitive.: Hygroscopic
• Water Solubility.: Soluble in water, alcohol, ether, hexane, benzene, methylcyclopentane, toluene, o-chlorotoluene and ethyl disulfide.

Purity/Quality:

99% ^*data from raw suppliers

Sodium methanesulfonate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: Sodium Methanesulfonate is used as a reactant in the preparation of indole acids as novel PDE2 inhibitors. It is also used as in the preparation of polyanionic antimicrobial membranes. Sodium methanesulfonate is generally used as an anion source [CH3SO3]? for synthesizing ionic liquids (PILs).

Technology Process of SODIUM METHANESULFONATE

There total 62 articles about SODIUM METHANESULFONATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

N,N-dimethylsulfonyl-O-methylhydroxylamine (80653-56-1) → methanesulfonic acid sodium salt (2386-57-4) + N-(methoxy)methanesulfonamide (80653-53-8)

Guidance literature:

With sodium hydroxide; In water; Product distribution; Mechanism; Heating; hydrolysis with basic, neutral and acidic aqu. solutions;

Reference yield: 93.0%

methanesulfonyl chloride (124-63-0) → methanesulfonic acid sodium salt (2386-57-4)

Guidance literature:

With sodium hydrogencarbonate; sodium sulfite; In water; at 20 ℃; for 2.25h;

DOI:10.1002/chem.202000899

Reference yield: 32.0%

sodium 2-oxopropane-1-sulfonate (16562-77-9) → sodium acetate (127-09-3) + methanesulfonic acid sodium salt (2386-57-4)

Guidance literature:

With sodium hydroxide; In water; for 6h; Heating;

upstream raw materials:

Methyl methanesulfonate

thiophenolate

4-nitrophenylthiolate

methanesulfonyl trimethylsilyl chloride

Downstream raw materials:

2-Methyl-benzoic acid 6-carbamimidoyl-naphthalen-2-yl ester; compound with methanesulfonic acid

Phenyl-acetic acid 6-carbamimidoyl-naphthalen-2-yl ester; compound with methanesulfonic acid

4-Sulfamoyl-benzoic acid 6-carbamimidoyl-naphthalen-2-yl ester; compound with methanesulfonic acid

4-Methylsulfanyl-benzoic acid 6-carbamimidoyl-naphthalen-2-yl ester; compound with methanesulfonic acid

Refernces

• 1、 Flyunt, Roman,Makogon, Oksana,Schuchmann, Man Nien,Asmus, Klaus-Dieter,Von Sonntag, Clemens. "OH-radical-induced oxidation of methanesulfinic acid. The reactions of the methanesulfonyl radical in the absence and presence of dioxygen". . p. 787 - 792. Retrieved 2001.
• 2、 Bayaraa, Tenuun,Kurz, Julia L.,Patel, Khushboo M.,Hussein, Waleed M.,Bilyj, Jessica K.,West, Nicholas P.,Schenk, Gerhard,McGeary, Ross P.,Guddat, Luke W.. "Discovery, Synthesis and Evaluation of a Ketol-Acid Reductoisomerase Inhibitor". . p. 8958 - 8968. Retrieved 2020/07/04.
• 3、 Chmayssem, Ayman,Taha, Samir,Hauchard, Didier. "Scaled-up electrochemical reactor with a fixed bed three-dimensional cathode for electro-Fenton process: Application to the treatment of bisphenol A". . p. 435 - 442. Retrieved 2017/01/09.