Technology Process of 2-Phenylnaphthalene-1-carbaldehyde
There total 8 articles about 2-Phenylnaphthalene-1-carbaldehyde which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
N-((2-methoxynaphthalen-1-yl)methylene)-tert-butylamine;
With
chromium dichloride;
In
tetrahydrofuran;
at 25 ℃;
for 0.0833333h;
Schlenk technique;
Inert atmosphere;
phenylmagnesium bromide;
In
tetrahydrofuran;
at 25 ℃;
for 5h;
Schlenk technique;
Inert atmosphere;
With
hydrogenchloride;
In
tetrahydrofuran; water;
at 25 ℃;
for 3h;
Schlenk technique;
Inert atmosphere;
DOI:10.1021/jacs.5b08621
- Guidance literature:
-
Multi-step reaction with 4 steps
1: Et3N / 1,2-dichloro-ethane
2: thionyl chloride / CH2Cl2; benzene / 4 h / Ambient temperature
3: 100 percent / tetrahydrofuran / Ambient temperature
4: 1.) methyl triflate, 2.) NaBH4, 3.) oxalic acid
With
sodium tetrahydroborate; thionyl chloride; oxalic acid; triethylamine; methyl trifluoromethanesulfonate;
In
tetrahydrofuran; dichloromethane; 1,2-dichloro-ethane; benzene;
DOI:10.1021/ja00029a032
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 1.) t-BuLi / 1.) THF, pentane, -78 deg C, 1 h, 2.) THF, pentane, from -78 deg C to RT, 1 h
2: oxalyl chloride / CH2Cl2 / 5 h
3: Et3N / 1,2-dichloro-ethane
4: thionyl chloride / CH2Cl2; benzene / 4 h / Ambient temperature
5: 100 percent / tetrahydrofuran / Ambient temperature
6: 1.) methyl triflate, 2.) NaBH4, 3.) oxalic acid
With
sodium tetrahydroborate; thionyl chloride; oxalyl dichloride; tert.-butyl lithium; oxalic acid; triethylamine; methyl trifluoromethanesulfonate;
In
tetrahydrofuran; dichloromethane; 1,2-dichloro-ethane; benzene;
DOI:10.1021/ja00029a032