Technology Process of Guanosine, 8-(acetyl(4'-(acetylamino)(1,1'-biphenyl)-4-yl)amino)-2'-deoxy-
There total 3 articles about Guanosine, 8-(acetyl(4'-(acetylamino)(1,1'-biphenyl)-4-yl)amino)-2'-deoxy- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium citrate; sodium chloride;
In
water; acetonitrile;
at 37 ℃;
for 6h;
pH=7.0;
DOI:10.1021/tx00047a011
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 20 percent aq. ammonium sulfide / dimethylformamide / 18 h / 5 °C
2: ethyl acetate; pyridine / 18 h / 5 °C
3: 24 percent / sodium chloride; sodium citrate / acetonitrile; H2O / 6 h / 37 °C / pH 7.0
With
ammonium sulfide; sodium citrate; sodium chloride;
In
pyridine; water; ethyl acetate; N,N-dimethyl-formamide; acetonitrile;
1: Reduction / 2: Acylation / 3: Substitution;
DOI:10.1021/tx00047a011
- Guidance literature:
-
Multi-step reaction with 2 steps
1: ethyl acetate; pyridine / 18 h / 5 °C
2: 24 percent / sodium chloride; sodium citrate / acetonitrile; H2O / 6 h / 37 °C / pH 7.0
With
sodium citrate; sodium chloride;
In
pyridine; water; ethyl acetate; acetonitrile;
1: Acylation / 2: Substitution;
DOI:10.1021/tx00047a011
