4,4-Dimethylandrost-5-ene-3,17-dione

Base Information

Chemical Name:4,4-Dimethylandrost-5-ene-3,17-dione
CAS No.:2220-48-6
Molecular Formula:C₂₁H₃₀O₂
Molecular Weight:314.468
Hs Code.:
NSC Number:85405
DSSTox Substance ID:DTXSID60944855
Wikidata:Q82922087
Mol file:2220-48-6.mol

Synonyms:2220-48-6;4,4-dimethylandrost-5-ene-3,17-dione;NSC85405;DTXSID60944855;NSC-85405

Suppliers and Price of 4,4-Dimethylandrost-5-ene-3,17-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 4,4-Dimethylandrost-5-ene-3,17-dione

Chemical Property:

Vapor Pressure:1.13E-07mmHg at 25°C
Boiling Point:432.2°Cat760mmHg
Flash Point:161.4°C
Density:1.08g/cm³
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:314.224580195
Heavy Atom Count:23
Complexity:613

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(C(=O)CCC2(C1=CCC3C2CCC4(C3CCC4=O)C)C)C
Isomeric SMILES:C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CC=C4[C@@]3(CCC(=O)C4(C)C)C

Technology Process of 4,4-Dimethylandrost-5-ene-3,17-dione

There total 5 articles about 4,4-Dimethylandrost-5-ene-3,17-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 63-05-8
4-androstene-3,17-dione

: 74-88-4
methyl iodide

: 2220-48-6
4,4-Dimethyl-5-Androsten-3,17-Dion

Guidance literature:: 4-androstene-3,17-dione; methyl iodide; With potassium tert-butylate; In tert-butyl alcohol; at 20 ℃; for 1h;

With sulfuric acid; water; In tert-butyl alcohol;

Reference yield:

: 5062-44-2
17β-hydroxy-4,4-dimethylandrost-5-en-3-one

: 2220-48-6
4,4-Dimethyl-androst-5-en-3,17-dion

Guidance literature:: With chromium(VI) oxide; sulfuric acid;
DOI:10.1039/j39660001847

Reference yield:

: 5062-42-0
17β-acetoxy-4,4-dimethyl-androst-5-en-3-one

: 2220-48-6
4,4-Dimethyl-androst-5-en-3,17-dion

Guidance literature:: Multi-step reaction with 2 steps

1: NaBH₄

2: (i) Pb(OAc)4, CaCO₃, (ii) AgNO₃, aq. NaOH, (iii) CrO₃, Py

With sodium tetrahydroborate;
DOI:10.1002/hlca.19620450741