3-Bromo-5-fluorobenzo[b]thiophene

Base Information

Chemical Name:3-Bromo-5-fluorobenzo[b]thiophene
CAS No.:138993-21-2
Molecular Formula:C8H4BrFS
Molecular Weight:231.088
Hs Code.:
European Community (EC) Number:882-058-4
Mol file:138993-21-2.mol

Synonyms:3-bromo-5-fluorobenzo[b]thiophene;138993-21-2;3-bromo-5-fluoro-1-benzothiophene;starbld0029191;SCHEMBL413347;3-bromo-5-fluoro-benzothiophene;HORROOAXKGNKAY-UHFFFAOYSA-N;F90344;EN300-3549023

Suppliers and Price of 3-Bromo-5-fluorobenzo[b]thiophene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 3-Bromo-5-fluorobenzo[b]thiophene

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:229.92011
Heavy Atom Count:11
Complexity:153

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC2=C(C=C1F)C(=CS2)Br

Technology Process of 3-Bromo-5-fluorobenzo[b]thiophene

There total 2 articles about 3-Bromo-5-fluorobenzo[b]thiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 70060-12-7
5-fluorobenzo[b]thiophene

: 138993-21-2
3-bromo-5-fluorobenzo[b]thiophene

Guidance literature:: With bromine; In dichloromethane; at 0 - 20 ℃; for 2h;
DOI:10.3390/molecules22030343

Reference yield:

: 70060-12-7
5-fluorobenzo[b]thiophene

Na₂ S₂ O₃: Na₂ S₂ O₃

: 138993-21-2
3-bromo-5-fluorobenzo[b]thiophene

Guidance literature:: With bromine; In tetrachloromethane; (2S)-N-methyl-1-phenylpropan-2-amine hydrate;

Reference yield: 88.0%

: 138993-21-2
3-bromo-5-fluorobenzo[b]thiophene

: 87199-17-5
4-formylphenylboronic acid,

: 4-(5-fluoro-1-benzothiophen-3-yl)benzaldehyde

Guidance literature:: 3-bromo-5-fluorobenzo[b]thiophene; With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; sodium carbonate; In 1,2-dimethoxyethane; for 0.0833333h; Inert atmosphere;

4-formylphenylboronic acid,; In 1,2-dimethoxyethane; ethanol; at 100 ℃; for 2h; Inert atmosphere; Microwave irradiation;
DOI:10.3390/molecules22030343