2-Hydroxy-4-(4-methylnaphthalen-1-yl)benzoic acid

Base Information

Chemical Name:2-Hydroxy-4-(4-methylnaphthalen-1-yl)benzoic acid
CAS No.:139082-29-4
Molecular Formula:C17H12O3
Molecular Weight:264.28
Hs Code.:
DSSTox Substance ID:DTXSID80695554
Wikidata:Q82624783

Synonyms:DTXSID80695554;2-hydroxy-4-(4-methylnaphthalen-1-yl)benzoic acid

Suppliers and Price of 2-Hydroxy-4-(4-methylnaphthalen-1-yl)benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-Hydroxy-4-(4-methylnaphthalen-1-yl)benzoic acid

Chemical Property:

XLogP3:4.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:278.094294304
Heavy Atom Count:21
Complexity:381

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C2=CC=CC=C12)C3=CC(=C(C=C3)C(=O)O)O

Technology Process of 2-Hydroxy-4-(4-methylnaphthalen-1-yl)benzoic acid

There total 3 articles about 2-Hydroxy-4-(4-methylnaphthalen-1-yl)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.5%

: 16870-28-3
4-iodosalicylic acid

: 13922-41-3
1-Naphthylboronic acid

: 139082-29-4
2-hydroxy-4-(naphthalen-1-yl)benzoic acid

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In ethanol; water; for 5h; Reflux; Inert atmosphere;
DOI:10.2147/DDDT.S319287

Reference yield:

: C₁₈H₁₄O₃

: 139082-29-4
2-hydroxy-4-(naphthalen-1-yl)benzoic acid

Guidance literature:: With sodium hydroxide; In 1,4-dioxane;
DOI:10.1016/j.bmcl.2014.02.010

Reference yield:

: 22717-56-2
4-bromo-2-Hydroxybenzoic Acid Methylester

: 13922-41-3
1-Naphthylboronic acid

: 139082-29-4
2-hydroxy-4-(naphthalen-1-yl)benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 1,1'-bis(diphenylphosphino)ferrocene-palladium(ii)dichloride-chloroform adduct; caesium carbonate / 1,4-dioxane; water

2: sodium hydroxide / 1,4-dioxane

With 1,1'-bis(diphenylphosphino)ferrocene-palladium(ii)dichloride-chloroform adduct; caesium carbonate; sodium hydroxide; In 1,4-dioxane; water;
DOI:10.1016/j.bmcl.2014.02.010