Methyl 4-bromo-2-hydroxybenzoate

Base Information

Chemical Name:Methyl 4-bromo-2-hydroxybenzoate
CAS No.:22717-56-2
Molecular Formula:C8H7 Br O3
Molecular Weight:231.046
Hs Code.:2918290000
European Community (EC) Number:607-144-9
DSSTox Substance ID:DTXSID80553807
Wikidata:Q82434489
Mol file:22717-56-2.mol

Synonyms:methyl 4-bromo-2-hydroxybenzoate;22717-56-2;methyl 4-bromo-2-hydroxybenzenecarboxylate;methyl 4-bromosalicylate;Methyl4-bromo-2-hydroxybenzoate;MFCD07780736;Benzoic acid, 4-bromo-2-hydroxy-, methyl ester;4-BROMO-2-HYDROXYBENZOIC ACID METHYL ESTER;SCHEMBL1378325;DTXSID80553807;JEMVEVUWSJXZMX-UHFFFAOYSA-N;CL8561;AKOS005072188;CS-W004803;DA-0608;SY029993;4-bromo-2-hydroxy-benzoic acid methyl ester;EN300-131319;A878463;Z862267138

Suppliers and Price of Methyl 4-bromo-2-hydroxybenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Methyl4-Bromo-2-hydroxybenzoate
50mg
$ 60.00

TRC
Methyl4-Bromo-2-hydroxybenzoate
10mg
$ 45.00

SynQuest Laboratories
Methyl 4-bromo-2-hydroxybenzoate
25 g
$ 365.00

SynQuest Laboratories
Methyl 4-bromo-2-hydroxybenzoate
5 g
$ 109.00

SynQuest Laboratories
Methyl 4-bromo-2-hydroxybenzoate
1 g
$ 29.00

Matrix Scientific
Methyl 4-bromo-2-hydroxybenzenecarboxylate >95%
1g
$ 39.00

Matrix Scientific
Methyl 4-bromo-2-hydroxybenzenecarboxylate >95%
5g
$ 119.00

Matrix Scientific
Methyl 4-bromo-2-hydroxybenzenecarboxylate >95%
25g
$ 385.00

Crysdot
Methyl4-bromo-2-hydroxybenzoate 98%
25g
$ 297.00

Chemenu
Methyl4-Bromosalicylate 95+%
25g
$ 281.00

Total 44 raw suppliers

Chemical Property of Methyl 4-bromo-2-hydroxybenzoate

Chemical Property:

Vapor Pressure:0.0017mmHg at 25°C
Melting Point:41-42°
Refractive Index:1.585
Boiling Point:284.7°C at 760 mmHg
PKA:8.79±0.10(Predicted)
Flash Point:126°C
PSA：46.53000
Density:1.627g/cm³
LogP:1.94130
Storage Temp.:Room temperature.
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:229.95786
Heavy Atom Count:12
Complexity:172

Purity/Quality:

98% ^*data from raw suppliers

Methyl4-Bromo-2-hydroxybenzoate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=C(C=C(C=C1)Br)O

Technology Process of Methyl 4-bromo-2-hydroxybenzoate

There total 3 articles about Methyl 4-bromo-2-hydroxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 67-56-1
methanol

: 1666-28-0
4-bromosalicylic acid

: 22717-56-2
4-bromo-2-Hydroxybenzoic Acid Methylester

Guidance literature:: With thionyl chloride; at 30 ℃; for 5h; Reagent/catalyst; Temperature;

Reference yield:

: 1666-28-0
4-bromosalicylic acid

: 18107-18-1
diazomethyl-trimethyl-silane

: 22717-56-2
4-bromo-2-Hydroxybenzoic Acid Methylester

Guidance literature:: In methanol; toluene; for 2h; Cooling with ice;

Reference yield:

: 65-49-6
4-Aminosalicylic acid

: 22717-56-2
4-bromo-2-Hydroxybenzoic Acid Methylester

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrogen bromide / water

1.2: 0.5 h / 0 °C

1.3: 1 h / 0 °C

2.1: sulfuric acid / methanol / 24 h / Heating / reflux

With sulfuric acid; hydrogen bromide; In methanol; water;