Phenazine, 1,6-dimethoxy-, 5,10-dioxide

Base Information

• Chemical Name: Phenazine, 1,6-dimethoxy-, 5,10-dioxide
• CAS No.: 13925-11-6
• Molecular Formula: C14H12N2O4
• ChEMBL ID: CHEMBL4217981
• DSSTox Substance ID: DTXSID80160979
• NSC Number: 742306
• Wikidata: Q83029340
• Mol file: 13925-11-6.mol

Synonyms:Phenazine, 1,6-dimethoxy-, 5,10-dioxide;13925-11-6;NSC742306;NSC 742306;CHEMBL4217981;SCHEMBL11716403;DTXSID80160979;CHEBI:192374;1,6-Dimethoxyphenanzine di-N-oxide;1,6-dimethoxyphenazine 5,10-dioxide;NSC-742306;1,6-dimethoxyphenazine N(5),N(10)-dioxide;1,6-dimethoxy-5,10-dioxido-phenazine-5,10-diium;1,6-dimethoxyphenazine-5,10-diium-5,10-bis(olate);1,6-dimethoxy-5,10-dioxo-5lambda(5),10lambda(5)-phenazine

Chemical Property of Phenazine, 1,6-dimethoxy-, 5,10-dioxide

Chemical Property:

• XLogP3: 1.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2
• Exact Mass: 272.07970687
• Heavy Atom Count: 20
• Complexity: 345

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=CC2=C1N(C3=C([N+]2=O)C(=CC=C3)OC)[O-]

Technology Process of Phenazine, 1,6-dimethoxy-, 5,10-dioxide

There total 1 articles about Phenazine, 1,6-dimethoxy-, 5,10-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

iodinin (68-81-5) + methyl iodide (74-88-4) → 1-hydroxy-6-methoxyphenazine N10-oxide (13129-57-2) + 1-hydroxy-6-methoxy-phenazine-N5,N10-dioxide (13925-12-7) + 1,6-dimethoxyphenazine-N5,N 10-dioxide (13925-11-6)

Guidance literature:

iodinin; With 18-crown-6 ether; potassium carbonate; In N,N-dimethyl-formamide; for 0.5h; Inert atmosphere;

methyl iodide; In N,N-dimethyl-formamide; at 20 ℃; for 24h; Temperature; Inert atmosphere;

DOI:10.1016/j.bmc.2017.02.058

Reference yield: 24.0%

1,6-dimethoxyphenazine-N5,N 10-dioxide (13925-11-6) → 1-hydroxy-6-methoxy-phenazine-N5,N10-dioxide (13925-12-7)

Guidance literature:

1,6-dimethoxyphenazine-N₅,N 10-dioxide; With aluminum (III) chloride; In dichloromethane; for 1.5h;

With hydrogenchloride; In dichloromethane; water;

DOI:10.1021/tx2004213

upstream raw materials:

iodinin

methyl iodide

Downstream raw materials:

1-hydroxy-6-methoxy-phenazine-N₅,N₁₀-dioxide