Morpholine, 4-[2-cyano-3-(4-methoxyphenyl)-1-oxo-2-propenyl]-

Base Information

Chemical Name:Morpholine, 4-[2-cyano-3-(4-methoxyphenyl)-1-oxo-2-propenyl]-
CAS No.:141736-04-1
Molecular Formula:C15H16N2O3
Molecular Weight:272.304
Hs Code.:
DSSTox Substance ID:DTXSID80384491

Synonyms:Morpholine, 4-[2-cyano-3-(4-methoxyphenyl)-1-oxo-2-propenyl]-;3-(4-methoxyphenyl)-2-(morpholine-4-carbonyl)prop-2-enenitrile;141736-04-1;DTXSID80384491

Suppliers and Price of Morpholine, 4-[2-cyano-3-(4-methoxyphenyl)-1-oxo-2-propenyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Morpholine, 4-[2-cyano-3-(4-methoxyphenyl)-1-oxo-2-propenyl]-

Chemical Property:

XLogP3:1.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:272.11609238
Heavy Atom Count:20
Complexity:410

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C=C(C#N)C(=O)N2CCOCC2

Technology Process of Morpholine, 4-[2-cyano-3-(4-methoxyphenyl)-1-oxo-2-propenyl]-

There total 2 articles about Morpholine, 4-[2-cyano-3-(4-methoxyphenyl)-1-oxo-2-propenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 110-91-8,99108-56-2
morpholine

: 1519-55-7
2-cyano-3-(4-methoxyphenyl)acrylic acid

: 141736-04-1
(Z)-3-(4-Methoxy-phenyl)-2-(morpholine-4-carbonyl)-acrylonitrile

Guidance literature:: With triethylamine; trichlorophosphate; In dichloromethane; at 0 - 20 ℃; for 8.5h;

Reference yield:

: 123-11-5
4-methoxy-benzaldehyde

: 141736-04-1
(Z)-3-(4-Methoxy-phenyl)-2-(morpholine-4-carbonyl)-acrylonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 59 percent / 70percent aq. perchloric acid, acetic acid / 96 h / 25 °C

2: 70 percent / phosphorus oxychloride, triethylamine / CH₂Cl₂ / 8.5 h / 0 - 20 °C

With perchloric acid; acetic acid; triethylamine; trichlorophosphate; In dichloromethane;