Furan, 2-cyclohexyl-

Base Information

• Chemical Name: Furan, 2-cyclohexyl-
• CAS No.: 14174-48-2
• Molecular Formula: C10H14O
• Molecular Weight: 150.221
• Mol file: 14174-48-2.mol

Synonyms:

Chemical Property of Furan, 2-cyclohexyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Furan, 2-cyclohexyl-

There total 12 articles about Furan, 2-cyclohexyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

4-(1-methoxycyclohexyl)but-3-yn-1-ol (1338347-15-1) → 2-cyclohexylfuran (14174-48-2)

Guidance literature:

With Zeise's dimer; In tetrahydrofuran; at 23 ℃; for 0.166667h; under 760.051 Torr; Inert atmosphere;

DOI:10.1021/ol202649j

Reference yield: 77.0%

Propiolaldehyde diethyl acetal (10160-87-9) + cyclohexanecarbaldehyde (2043-61-0) → 2-cyclohexylfuran (14174-48-2)

Guidance literature:

Propiolaldehyde diethyl acetal; With n-butyllithium; In diethyl ether; hexane; at 20 ℃; for 1h;

cyclohexanecarbaldehyde; With titanium(IV) isopropylate; isopropylmagnesium chloride; In diethyl ether; hexane; at -40 - -35 ℃; for 2.5h;

With hydrogenchloride; Further stages.;

DOI:10.3987/com-07-11017

Reference yield: 75.0%

2-bromofuran (584-12-3) + Cyclohexyl iodide (626-62-0) → 2-cyclohexylfuran (14174-48-2)

Guidance literature:

With 1,2-bis(diphenylphosphino)ethane nickel(II) chloride; iodine; magnesium; In diethyl ether; at -2 ℃; for 22h; Inert atmosphere; Reflux;

DOI:10.1002/chem.201404903

upstream raw materials:

3,4-Dichloro-1-cyclohexyl-butan-1-one

3-chloroprop-1-ene

cyclohexanylcarbonyl chloride

Propiolaldehyde diethyl acetal

Refernces

• 1、 Marinelli,Levy. "". . p. 2313. Retrieved 1979.
• 2、 Allegretti, Paul A.,Ferreira, Eric M.. "Generation of α,β-unsaturated platinum carbenes from homopropargylic alcohols: Rearrangements to polysubstituted furans". . p. 5924 - 5927. Retrieved 2011/12/16.